Clathrin-independent carriers (CLICs) are prevalent tubulovesicular membranes responsible for non-
clathrin
Clathrin is a protein that plays a major role in the formation of coated vesicles. Clathrin was first isolated and named by Barbara Pearse in 1976. It forms a triskelion shape composed of three clathrin heavy chains and three light chains. When ...
mediated
endocytic events. They appear to endocytose material into
GPI-anchored protein
Lipid-anchored proteins (also known as lipid-linked proteins) are proteins located on the surface of the cell membrane that are covalently attached to lipids embedded within the cell membrane. These proteins insert and assume a place in the bilay ...
-enriched early
endosomal compartment (
GEECs). Collectively, CLICs and GEECs comprise the
Cdc42-mediated
CLIC/GEEC endocytic pathway, which is regulated by
GRAF1.
References
Peripheral membrane proteins
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