{{Infobox company , , name = Cyclacel Pharmaceuticals, Inc. , logo = Cyclacel.png , type = Public , traded_as = {{NASDAQ, CYCC , foundation = 1997 , location =

Berkeley Heights, New Jersey Berkeley Heights is a township in Union County, New Jersey, United States. A commuter town in northern-central New Jersey, the township is nestled within the Raritan Valley region in the New York metropolitan area. As of the 2010 United States ...

, U.S. , key_people =

Spiro Rombotis Spiro(s) may refer to: * Spiro, Oklahoma, a town in the U.S. ** Spiro Mounds, an archaeological site * Spiro (band), a British music group * Spiro (name), including a list of people with the name * Špiro, South Slavic masculine given name * ARA ...

, CEO
David P. Lane, PhD, founder

Paul McBarron Paul may refer to: *Paul (given name), a given name (includes a list of people with that name) *Paul (surname), a list of people People Christianity * Paul the Apostle (AD c.5–c.64/65), also known as Saul of Tarsus or Saint Paul, early Chri ...

, EVP, Finance & COO

Mark Kirschbaum, MD Mark may refer to: Currency * Bosnia and Herzegovina convertible mark, the currency of Bosnia and Herzegovina * East German mark, the currency of the German Democratic Republic * Estonian mark, the currency of Estonia between 1918 and 1927 * Fi ...

, CMO , industry =

Biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

, products = Fadraciclib (formerly CYC065),
CYC140 , net_income = {{loss US$ 19.1 million (2021) , num_employees = 17 (2022) , homepage = http://www.cyclacel.com Cyclacel Pharmaceuticals Inc. is a

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

firm based in

and

Dundee Dundee (; sco, Dundee; gd, Dùn Dè or ) is Scotland's fourth-largest city and the 51st-most-populous built-up area in the United Kingdom. The mid-year population estimate for 2016 was , giving Dundee a population density of 2,478/km2 or ...

, Scotland, developing cancer treatments. Cyclacel was founded in 1996 by David Lane, PhD.

Company overview

Cyclacel Pharmaceuticals, Inc. is a clinical-stage, biopharmaceutical company developing innovative cancer medicines based on cell cycle, transcriptional regulation and mitosis biology. The transcriptional regulation program is evaluating fadraciclib, a CDK2/9 inhibitor, and the anti-mitotic program CYC140, a PLK1 inhibitor, in patients with both solid tumors and hematological malignancies. Cyclacel’s strategy is to build a diversified biopharmaceutical business based on a pipeline of novel drug candidates addressing oncology and hematology indications. For additional information, please visit www.cyclacel.com. Sir David Lane, PhD, a recognized leader in the field of tumor suppressor biology, who discovered the p53 protein, founded the company in 1996. In 1999, Cyclacel Pharmaceuticals was joined by David Glover, PhD, a recognized leader in the mechanism of mitosis or cell division, who discovered, among other cell cycle targets, the mitotic kinases, Polo and Aurora, enzymes that act in the mitosis phase of the cell cycle. Companies listed on the Nasdaq Pharmaceutical companies based in New Jersey Pharmaceutical companies of Scotland Companies based in Dundee Science and technology in Dundee