The first cyanobacterial RNA thermometer ( RNAT) Hsp17 was found in the 5'UTR of '' Synechocystis'' heat shock ''hsp17'' mRNA. Further study demonstrated that cyanobacteria commonly use RNATs to control the translation of their heat shock genes. HspA is a homolog of Hsp17 in thermophilic ''

Thermosynechococcus elongatus ''Synechococcus'' (from the Greek ''synechos'', in succession, and the Greek ''kokkos'', granule) is a unicellular cyanobacterium that is very widespread in the marine environment. Its size varies from 0.8 to 1.5 µm. The photosynthetic c ...

''. Two more thermometers were found in the 5'UTRs of mesophilic cyanobacteria '' A. variabilis'' and '' Nostoc'' ''sp''. The first RNAT called avashort was shown to regulate translation by masking the AUG translation start site. The second RNAT called avalong, as it has an extended initial hairpin, might involve tertiary interactions and has similarities to the

ROSE element The repression of heat shock gene expression (ROSE) element is an RNA element found in the 5' UTR of some heat shock protein's mRNAs. The ROSE element is an RNA thermometer that negatively regulates heat shock gene expression. The secondary s ...

References

Non-coding RNA Cis-regulatory RNA elements {{molecular-cell-biology-stub