''Cunninghamella blakesleeana'' is a fungus species in the genus ''
Cunninghamella
Cunninghamella is a genus of fungi in the order Mucorales, and the family Cunninghamellaceae. The genus was circumscribed by French mycologist Alphonse Louis Paul Matruchot in Ann. Mycol. Vol.1 on page 47 in 1903.
The genus name of ''Cunning ...
''.
Biotechnology use
Microbiological
oxidation
Redox (reduction–oxidation, , ) is a type of chemical reaction in which the oxidation states of substrate change. Oxidation is the loss of electrons or an increase in the oxidation state, while reduction is the gain of electrons or a d ...
of
steroid
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and a ...
s has been studied using ''Cunninghamella blakesleeana'' H-334.
''Cunninghamella blakesleeana'' has been used to transform
cortexolone
11-Deoxycortisol, also known as cortodoxone (INN), cortexolone as well as 17α,21-dihydroxyprogesterone or 17α,21-dihydroxypregn-4-ene-3,20-dione, is an endogenous glucocorticoid steroid hormone, and a metabolic intermediate towards cortisol. It ...
to
hydrocortisone
Hydrocortisone is the name for the hormone cortisol when supplied as a medication. Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, ...
.
References
External links
Cunninghamellaceae
Fungi described in 1927
{{zygomycota-stub