Crucial Experiment
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In science, an ''experimentum crucis'' (
English English usually refers to: * English language * English people English may also refer to: Peoples, culture, and language * ''English'', an adjective for something of, from, or related to England ** English national ide ...
: crucial experiment or critical experiment) is an
experiment An experiment is a procedure carried out to support or refute a hypothesis, or determine the efficacy or likelihood of something previously untried. Experiments provide insight into Causality, cause-and-effect by demonstrating what outcome oc ...
capable of decisively determining whether or not a particular
hypothesis A hypothesis (plural hypotheses) is a proposed explanation for a phenomenon. For a hypothesis to be a scientific hypothesis, the scientific method requires that one can test it. Scientists generally base scientific hypotheses on previous obse ...
or
theory A theory is a rational type of abstract thinking about a phenomenon, or the results of such thinking. The process of contemplative and rational thinking is often associated with such processes as observational study or research. Theories may be s ...
is superior to all other hypotheses or theories whose acceptance is currently widespread in the scientific community. In particular, such an experiment must typically be able to produce a result that rules out all other hypotheses or theories if true, thereby demonstrating that under the conditions of the experiment (''i.e.'', under the same external circumstances and for the same "input variables" within the experiment), those hypotheses and theories are ''proven false'' but the experimenter's hypothesis ''is not ruled out''. For an opposite view putting into question the decisive value of the ''experimentum crucis'' in choosing one hypothesis or theory over its rivals, see
Pierre Duhem Pierre Maurice Marie Duhem (; 9 June 1861 – 14 September 1916) was a French theoretical physicist who worked on thermodynamics, hydrodynamics, and the theory of elasticity. Duhem was also a historian of science, noted for his work on the Euro ...
.


History

Francis Bacon Francis Bacon, 1st Viscount St Alban (; 22 January 1561 – 9 April 1626), also known as Lord Verulam, was an English philosopher and statesman who served as Attorney General and Lord Chancellor of England. Bacon led the advancement of both ...
in his '' Novum Organum'' first described the concept of a situation in which one theory but not others would hold true, using the name ''instantia crucis''; the phrase ''experimentum crucis'', denoting the deliberate creation of such a situation for the purpose of testing the rival theories, was later coined by
Robert Hooke Robert Hooke FRS (; 18 July 16353 March 1703) was an English polymath active as a scientist, natural philosopher and architect, who is credited to be one of two scientists to discover microorganisms in 1665 using a compound microscope that ...
and then famously used by
Isaac Newton Sir Isaac Newton (25 December 1642 – 20 March 1726/27) was an English mathematician, physicist, astronomer, alchemist, theologian, and author (described in his time as a "natural philosopher"), widely recognised as one of the grea ...
. The production of such an experiment is considered necessary for a particular hypothesis or theory to be considered an established part of the body of scientific knowledge. It is not unusual in the history of science for theories to be developed fully before producing a critical experiment. A given theory which is in accordance with known experiment but which has not yet produced a critical experiment is typically considered worthy of exploration in order to discover such an experimental test.


Examples

Robert Boyle Robert Boyle (; 25 January 1627 – 31 December 1691) was an Anglo-Irish natural philosopher, chemist, physicist, alchemist and inventor. Boyle is largely regarded today as the first modern chemist, and therefore one of the founders of ...
was the first person to hail an experiment as ''experimentum crucis'' when he referred to the famous mercury barometer experiment on Puy-de-Dome in 1648. This experiment settled the question: Was there some natural resistance to the creation of an apparently empty space at the top of the tube, or was the height of the mercury determined solely by the weight of the air? In his ''
Philosophiæ Naturalis Principia Mathematica (English: ''Mathematical Principles of Natural Philosophy'') often referred to as simply the (), is a book by Isaac Newton that expounds Newton's laws of motion and his law of universal gravitation. The ''Principia'' is written in Latin and ...
'',
Isaac Newton Sir Isaac Newton (25 December 1642 – 20 March 1726/27) was an English mathematician, physicist, astronomer, alchemist, theologian, and author (described in his time as a "natural philosopher"), widely recognised as one of the grea ...
(1687) presents a disproof of
Descartes' vortex theory Mechanical explanations of gravitation (or kinetic theories of gravitation) are attempts to explain the action of gravity by aid of basic mechanical processes, such as pressure forces caused by pushes, without the use of any action at a distance. ...
of the motion of the planets. In his ''
Opticks ''Opticks: or, A Treatise of the Reflexions, Refractions, Inflexions and Colours of Light'' is a book by English natural philosopher Isaac Newton that was published in English in 1704 (a scholarly Latin translation appeared in 1706). (''Optick ...
'', Newton describes an optical ''experimentum crucis'' in the ''First Book, Part I, Proposition II, Theorem II, Experiment 6'', to prove that sunlight consists of rays that differ in their
index of refraction In optics, the refractive index (or refraction index) of an optical medium is a dimensionless number that gives the indication of the light bending ability of that medium. The refractive index determines how much the path of light is bent, or ...
. A 19th-century example was the prediction by Poisson, based on Fresnel's mathematical analysis, that the
wave theory of light In physics, physical optics, or wave optics, is the branch of optics that studies Interference (wave propagation), interference, diffraction, Polarization (waves), polarization, and other phenomena for which the ray approximation of geometric opti ...
predicted a bright spot in the center of the shadow of a perfectly circular object, a result that could not be explained by the (then current) particle theory of light. An experiment by
François Arago Dominique François Jean Arago ( ca, Domènec Francesc Joan Aragó), known simply as François Arago (; Catalan: ''Francesc Aragó'', ; 26 February 17862 October 1853), was a French mathematician, physicist, astronomer, freemason, supporter of t ...
showed the existence of this effect, now called the
Arago spot Arago may refer to: People * Aragó, a family name of the kings of the Aragonese Crown * Étienne Arago (1802–1892), French journalist, theater director, and politician; brother of Juan, François, and Jacques * François Arago (1786–1853), F ...
, or "Poisson's bright spot", which led to the acceptance of the wave theory. A famous example in the 20th century of an ''experimentum crucis'' was the expedition led by
Arthur Eddington Sir Arthur Stanley Eddington (28 December 1882 – 22 November 1944) was an English astronomer, physicist, and mathematician. He was also a philosopher of science and a populariser of science. The Eddington limit, the natural limit to the lumin ...
to Principe Island in
Africa Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area ...
in 1919 to record the positions of stars around the Sun during a
solar eclipse A solar eclipse occurs when the Moon passes between Earth and the Sun, thereby obscuring the view of the Sun from a small part of the Earth, totally or partially. Such an alignment occurs during an eclipse season, approximately every six month ...
(see Eddington experiment). The observation of star positions confirmed predictions of
gravitational lensing A gravitational lens is a distribution of matter (such as a galaxy cluster, cluster of galaxies) between a distant light source and an observer that is capable of bending the light from the source as the light travels toward the observer. This ...
made by
Albert Einstein Albert Einstein ( ; ; 14 March 1879 – 18 April 1955) was a German-born theoretical physicist, widely acknowledged to be one of the greatest and most influential physicists of all time. Einstein is best known for developing the theory ...
in the general theory of relativity published in 1915. Eddington's observations were considered to be the first solid evidence in favor of Einstein's theory. In some cases, a proposed theory can account for existing anomalous experimental results for which no other existing theory can furnish an explanation. An example would be the ability of the quantum hypothesis, proposed by Max Planck in 1900, to account for the observed
black-body spectrum A black body or blackbody is an idealized physical body that absorbs all incident electromagnetic radiation, regardless of frequency or angle of incidence. The name "black body" is given because it absorbs all colors of light. A black body ...
, an experimental result that the existing classical Rayleigh–Jeans law could not predict. Such cases are not considered strong enough to fully establish a new theory, however, and in the case of quantum mechanics, it took the confirmation of the theory through ''new'' predictions for the theory to gain full acceptance.


DNA, experimentum crucis

:''See §Context for crucial experiment in the discovery of the §structure of DNA, and §List of experiments in biology'' In the discovery of the significance of the structure of DNA, the fact that DNA was a double helix enabled the discoverers, Francis Crick and James Watson, to suggest that one strand of the double helix could serve as the template for the second strand, as the second strand was being duplicated. This explained the ''secret of life'', how the structure of DNA could serve as the
mechanism Mechanism may refer to: *Mechanism (engineering), rigid bodies connected by joints in order to accomplish a desired force and/or motion transmission *Mechanism (biology), explaining how a feature is created *Mechanism (philosophy), a theory that a ...
for the
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
(the genetic code), in which four
nucleotide Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules wi ...
s serve to encode the sequence of
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
s needed to catalyze the production of macromolecules in the cell, and which led to its application in synthetic biology, in
genetic engineering Genetic engineering, also called genetic modification or genetic manipulation, is the modification and manipulation of an organism's genes using technology. It is a set of technologies used to change the genetic makeup of cells, including t ...
, in
forensics Forensic science, also known as criminalistics, is the application of science to criminal and civil laws, mainly—on the criminal side—during criminal investigation, as governed by the legal standards of admissible evidence and crimina ...
,
genetic testing Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, or ...
,
genomics Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...
and
pharmaceutical A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and re ...
s, among other industries.


Tanis fossil site

In the 21st century, the discovery of the Tanis fossil site, a killing field in the Hell Creek formation of North Dakota, proved that the K-T boundary (now known as the KPg, or the
Cretaceous–Paleogene extinction event The Cretaceous–Paleogene (K–Pg) extinction event (also known as the Cretaceous–Tertiary extinction) was a sudden mass extinction of three-quarters of the plant and animal species on Earth, approximately 66 million years ago. With the ...
) was the same event (the Chicxulub impact) which killed off the
dinosaur Dinosaurs are a diverse group of reptiles of the clade Dinosauria. They first appeared during the Triassic period, between 243 and 233.23 million years ago (mya), although the exact origin and timing of the evolution of dinosaurs is t ...
s. This
impact event An impact event is a collision between astronomical objects causing measurable effects. Impact events have physical consequences and have been found to regularly occur in planetary systems, though the most frequent involve asteroids, comets or me ...
was previously hypothesized from the global existence of
iridium Iridium is a chemical element with the symbol Ir and atomic number 77. A very hard, brittle, silvery-white transition metal of the platinum group, it is considered the second-densest naturally occurring metal (after osmium) with a density of ...
deposits (a rare element on Earth). In this case, the existence of a microtektite layer raining down upon the multiple intermixed species (including a
Triceratops ''Triceratops'' ( ; ) is a genus of herbivore, herbivorous Chasmosaurinae, chasmosaurine Ceratopsidae, ceratopsid dinosaur that first appeared during the late Maastrichtian stage of the Late Cretaceous Period (geology), period, about 68 m ...
) which were found at the site (the Tanis Konservat-Lagerstätte) served as the conclusive witness, as cited in ''Science Daily''.University of California - Berkeley: (29 March 2019) 66-million-year-old deathbed linked to dinosaur-killing meteor
/ref> Based on the dating of the Tanis, the event occurred 65.76 million years ago (± 0.15 My).


See also

* Contraposition in logic, the formal basis of an ''experimentum crucis'' * Cross-validation (disambiguation) * Falsifiability * Material conditional *
Q.E.D. Q.E.D. or QED is an initialism of the Latin phrase , meaning "which was to be demonstrated". Literally it states "what was to be shown". Traditionally, the abbreviation is placed at the end of mathematical proofs and philosophical arguments in pri ...
*
Scientific method The scientific method is an empirical method for acquiring knowledge that has characterized the development of science since at least the 17th century (with notable practitioners in previous centuries; see the article history of scientific m ...
*
Smoking gun The term "smoking gun" is a reference to an object or fact that serves as conclusive evidence of a crime or similar act, just short of being caught ''in flagrante delicto''. "Smoking gun" refers to the strongest kind of circumstantial evidence, ...
* Therefore sign


Notes

{{Authority control Scientific method