Crome syndrome is a rare disease defined by various symptoms, including epilepsy, intellectual disability,

eye Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and conv ...

and kidney problems. It usually causes death in 4 to 8 months.

History

In 1963, a doctor studied two female

infant An infant or baby is the very young offspring of human beings. ''Infant'' (from the Latin word ''infans'', meaning 'unable to speak' or 'speechless') is a formal or specialised synonym for the common term ''baby''. The terms may also be used to ...

s who showed symptoms of intellectual disability, congenital cataracts, epileptic seizures and small stature. The two girls died at the age of 4 and 8 months. The

autopsy An autopsy (post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any di ...

revealed renal

tubular necrosis Acute tubular necrosis (ATN) is a medical condition involving the death of tubular epithelial cells that form the renal tubules of the kidneys. Because necrosis is often not present, the term acute tubular injury (ATI) is preferred by pathologists ...

and encephalopathy.

References

External links

Syndromes affecting the eye Rare syndromes Syndromes affecting stature {{nervoussystem-disease-stub