Cowdry bodies are
eosinophilic
Eosinophilic (Greek suffix -phil-, meaning ''loves eosin'') is the staining of tissues, cells, or organelles after they have been washed with eosin, a dye.
Eosin is an acidic dye for staining cell cytoplasm, collagen, and muscle fibers. ''E ...
or basophilic nuclear inclusions composed of
nucleic acid and protein seen in cells infected with
Herpes simplex virus,
Varicella-zoster virus
Varicella-zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or ''Human alphaherpesvirus 3'' (taxonomically), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting chil ...
, and
Cytomegalovirus. They are named after Edmund Cowdry.
There are two types of intranuclear Cowdry bodies:
* Type A (as seen in herpes simplex and VZV)
* Type B (as seen in infection with poliovirus and CMV), though it may seem that this is an antiquated and perhaps illusory type.
is used for detection of Cowdry bodies.
References
Histopathology
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