Covid-19 Hospital
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COVID-19 hospital is a general name given to clinical institutions that provide medical treatment to Coronavirus Disease 2019 (COVID-19) infected patients. According to the World Health Organisation (WHO)'s COVID-19 regulations, it is critical to distribute COVID-19 patients to different medical institutions based on their severity of symptoms and the medical resource availability in different geographical regions. It is recommended by the WHO to distribute patients with the most severe symptoms to the most equipped, COVID-19 focused hospitals, then patients with less severe symptoms to local institutions and lastly, patients with light symptoms to temporary COVID-19 establishments for appropriate isolation and monitoring of disease progression. Countries, like
China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...
,
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
,
Russia Russia (, , ), or the Russian Federation, is a List of transcontinental countries, transcontinental country spanning Eastern Europe and North Asia, Northern Asia. It is the List of countries and dependencies by area, largest country in the ...
,
the United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
and
the United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...
have established their distinctive COVID-19 clinical set-ups based on the general WHO guidelines. Future pandemic protocols have also been adapted based on handling COVID-19 on a national and global scale.


COVID-19 Hospital Protocols


Protective regulations for healthcare staff

Healthcare staff at designated COVID-19 hospitals are protected with the personal protective equipment (PPE), which includes coveralls, masks, eye protector and gloves. Hospitals have strict regulations for the healthcare staff on disposing of the PPE. The protective wear must be worn at all times when coming in contact with COVID-19 patients and must be taken off after leaving the COVID-19 wards.


Testing of SARS-CoV-2 virus prior to hospitalisation

Prior to the hospitalisation, patients have to take a series of examinations to test for the presence of SARS-CoV-2 virus in their body. Patients can provide samples of their
sputum Sputum is mucus that is coughed up from the lower airways (the trachea and bronchi). In medicine, sputum samples are usually used for a naked eye examination, microbiological investigation of respiratory infections and cytological investigations ...
,
faeces Feces ( or faeces), known colloquially and in slang as poo and poop, are the solid or semi-solid remains of food that was not digested in the small intestine, and has been broken down by bacteria in the large intestine. Feces contain a relati ...
or
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
for
COVID-19 testing COVID-19 testing involves analyzing samples to assess the current or past presence of SARS-CoV-2. The two main types of tests detect either the presence of the virus or antibodies produced in response to infection. Molecular tests for viral ...
. In sputum samples, the virus can be observed 1 to 2 days before the appearance of symptoms and can remain detectable in the body for up to around 2 weeks. In fecal samples, the virus can be detected starting from the fifth day after the onset of symptoms and remains detectable in the body for about a month. Alternatively, a
serological test Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given m ...
can be performed to see if the patients contain COVID-19
antibodies An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...
in their blood. The blood test identifies the development of different
immunoglobulins An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the ...
(
IgM Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antig ...
,
IgG Immunoglobulin G (Ig G) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. IgG molecules are created and released by plasma B cells. Each IgG ...
and IgM+IgG) in COVID-19 recovered patients.


Patients release protocols

Guidelines are available to help medical professionals determine which patients are suitable to be released from the hospital. For example, a patient needs to be
afebrile Normal human body-temperature (normothermia, euthermia) is the typical temperature range found in humans. The normal human body temperature range is typically stated as . Human body temperature varies. It depends on sex, age, time of day, exert ...
for more than 3 days, to show improvements of symptoms, to have satisfactory improvements shown in the X-ray scan of his or her lungs and to have 2 consecutive negative PCR tests on the same day. Even after the official hospital discharge, the patient needs to remain socially distanced to their family members and friends, as the risk of infecting others is not eliminated.


COVID-19 Hospitals By Region


China

Different regions in China have their designated COVID-hospitals, either transformed from normal hospitals or from large sports halls and exhibition centres. Wuhan, the first recognised region of
COVID-19 outbreak The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identified ...
, has established 45 COVID-19 hospitals. Among the 45 hospitals, 6 of them provide healthcare services to critically endangered patients, and the remaining 39 hospitals offer treatment to severely ill patients and patients who are older than 65 years old. Lastly, patients with less severe symptoms are treated in large sports hall- or exhibition centre- converted hospitals. The exact number of temporary COVID-19 hospitals in Wuhan is unknown, but the number of beds made available to patients has at least increased to more than 50,000.


COVID-19 Treatment in hospitals in China

In China, the National Health Commission (NHC) has launched the National Clinical guidelines (6th edition) to lay out the specific treatments and regulations for handling COVID-19 patients. The four main policies of the Chinese National Health Commission aim to achieve minimal COVID-19 fatality in COVID-19 hospitals. # To localise patients in hospitals that are designated to treat COVID-19 # To recruit medical experts in the COVID-19 hospitals # To obtain sufficient medical resources in COVID-19 hospitals # To be able to provide COVID-19 treatment in designated hospitals All patients once hospitalised, their blood oxygen levels are constantly monitored. Depending on the severity of their disease progression, they will receive different levels of supportive care, e.g.
pharmacological agent An active ingredient is any ingredient that provides biological activity, biologically active or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the body of h ...
s to help them fight against the viral
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
in the body. Some drug examples include
chloroquine Chloroquine is a medication primarily used to prevent and treat malaria in areas where malaria remains sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medi ...
,
phosphate In chemistry, a phosphate is an anion, salt, functional group or ester derived from a phosphoric acid. It most commonly means orthophosphate, a derivative of orthophosphoric acid . The phosphate or orthophosphate ion is derived from phospho ...
,
lopinavir Lopinavir is an antiretroviral of the protease inhibitor class. It is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir (lopinavir/ritonavir). It was patented in 1995 and approved for medical ...
or
ritonavir Ritonavir, sold under the brand name Norvir, is an antiretroviral drug used along with other medications to treat HIV/AIDS. This combination treatment is known as highly active antiretroviral therapy (HAART). Ritonavir is a protease inhibitor a ...
,
alpha interferon The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses. In the human genome, a cluster of thirteen functional IFN genes is located at the 9p21.3 cyt ...
,
ribavirin Ribavirin, also known as tribavirin, is an antiviral medication used to treat RSV infection, hepatitis C and some viral hemorrhagic fevers. For hepatitis C, it is used in combination with other medications such as simeprevir, sofosbuvir, pegin ...
and
arbidol Umifenovir, sold under the brand name Arbidol, is an antiviral medication for the treatment of influenza and COVID infections used in Russia and China. The drug is manufactured by Pharmstandard (russian: Фармстандарт). It is not ...
. The dosage and dosing frequency are dependent on the individual patient's disease progression. For more severely-ill patients,
intubation Intubation (sometimes entubation) is a medical procedure involving the insertion of a tube into the body. Patients are generally anesthetized beforehand. Examples include tracheal intubation, and the balloon tamponade with a Sengstaken-Blakemo ...
or invasive ventilation and extracorporeal membrane oxygen (ECMO) are used to enhance their chance of survival. ECMO is used to transfuse the patient's blood out of the body and perform oxygenation of the blood with the help of a machine. This method could alleviate the disease burden on the patients and allow the
cardiovascular The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, tha ...
and
respiratory system The respiratory system (also respiratory apparatus, ventilatory system) is a biological system consisting of specific organs and structures used for gas exchange in animals and plants. The anatomy and physiology that make this happen varies grea ...
s to recover. It has been reported that the use of ECMO has shown health improvement in 3 out of 4 critically ill patients. In China, patients also receive
traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action ...
as part of their therapeutic regimen. However, there is limited understanding on evaluating the efficacy of these drugs while they are used in combination with western drugs and or other mechanical supportive equipment.


Germany

Despite its relative adequateness of intensive care beds compared to other European nations, plans were drafted by the federal and state governments of Germany to further expand care capacity for COVID-19 patients as the pandemic broke out. These plans include the conversion of community halls and hotels, when needed, into COVID-19 centres for treatment of patients with mild conditions. On March 17, 2020, the local government in
Berlin Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constitue ...
announced plans to convert one exhibition hall in the
Messe Berlin Messe Berlin (') are exhibition grounds in the Charlottenburg-Wilmersdorf precinct of Berlin, Germany, at Masurenallee opposite the Haus des Rundfunks. Since 2011, they have officially been known as "Berlin ExpoCenter City" and operated by the M ...
exhibition grounds at the capital's
Charlottenburg-Wilmersdorf Charlottenburg-Wilmersdorf () is the fourth borough of Berlin, formed in an administrative reform with effect from 1 January 2001, by merging the former boroughs of Charlottenburg and Wilmersdorf. Overview Charlottenburg-Wilmersdorf covers the w ...
precinct into a temporary hospital containing 1000 beds. The hospital should have the capabilities to treat both minor and emergency COVID-19 cases; but it is only expected to enter service when current hospitals are full. Construction of the hospital began on April 1, with assistance from the
German armed forces The ''Bundeswehr'' (, meaning literally: ''Federal Defence'') is the armed forces of the Federal Republic of Germany. The ''Bundeswehr'' is divided into a military part (armed forces or ''Streitkräfte'') and a civil part, the military part con ...
. The first phase of construction would provide 500 beds, with 500 more ready to be added.


Hong Kong

Hospital care for COVID-19 patients in Hong Kong at the beginning of the
pandemic A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic (epidemiology), endemic disease wi ...
was provided by existing isolation wards in the city's hospitals. With the number of existing wards being unable to accommodate the increasing patient numbers, the Hong Kong Hospital Authority (HA) sought to convert other wards and community facilities for COVID-19 treatment. For ward conversions, general wards in public hospitals were converted into standard negative pressure isolation wards in two phases, which by August 2020 lifted the total isolation bed capacity to 660. For conversion of community facilities, the AsiaWorld-Expo in
Lantau Island Lantau Island (also Lantao Island, Lan Tao) is the largest island in Hong Kong, located West of Hong Kong Island and the Kowloon Peninsula, and is part of the New Territories. Administratively, most of Lantau Island is part of the Islands ...
has been used as a “community treatment facility” since August 1, 2020, with the venue converted to fit 900 beds to provide isolation and treatment for COVID-19 patients with mild symptoms and stable conditions. As of March 2021, the facility is put on standby due to low current demand for beds; however, it can be reactivated into service within 72 hours. On August 10, 2020, the Hong Kong government announced plans to construct a temporary hospital at
Chek Lap Kok Chek Lap Kok is an island in the western waters of Hong Kong's New Territories. Unlike the smaller Lam Chau, it was only partially leveled when it was assimilated via land reclamation into the island for the current Hong Kong International ...
, Lantau Island, next to the AsiaWorld-Expo. The proposed hospital comprises 6 blocks, each being two-storey buildings, providing 800 to 1000 beds in isolation wards and medical facilities to treat COVID-19 patients with “suitable clinical conditions”. The wards and its facilities effectively free up beds in isolation wards of public hospitals as it offers hospital-grade intravenous medications and
oxygen therapy Oxygen therapy, also known as supplemental oxygen, is the use of oxygen as medical treatment. Acute indications for therapy include hypoxemia (low blood oxygen levels), carbon monoxide toxicity and cluster headache. It may also be prophylactica ...
. Construction of the hospital began in October 2020, and was completed in four months, with the number of provided beds confirmed at 816. The facility, named the North Lantau Hospital Hong Kong Infection Control Centre, was handed over to the HA in January 2021 for opening preparations, and patient admissions officially began on February 26.


Russia

Hospital services in many parts of Russia are under pressure amidst increased patient numbers and poor facilities as the pandemic hit. The strain is particularly heavy in the country's capital,
Moscow Moscow ( , US chiefly ; rus, links=no, Москва, r=Moskva, p=mɐskˈva, a=Москва.ogg) is the capital and largest city of Russia. The city stands on the Moskva River in Central Russia, with a population estimated at 13.0 million ...
, where they are more equipped than any other region countrywide, but also having by far the highest patient numbers. To alleviate this strain, the local Moscow government started the construction of temporary hospitals in the suburbs of Moscow in mid-2020, mostly near existing large clinics. Most buildings were not converted from existing infrastructure, but built from scratch. By late-October 2020, Moscow has around 50 temporary hospitals in operation, providing 3000 beds. One of the few converted hospitals is located at the Krylatskoye Ice Palace, an indoor ice arena most known for hosting international ice skating tournaments, including the
2005 World Allround Speed Skating Championships The 2005 World Allround Speed Skating Championships were held in the indoor arena in Moscow, Russia, on 5 and 6 February 2005. German Anni Friesinger and American Shani Davis Shani Earl Davis (; born August 13, 1982) is an American former spe ...
. It was converted and began operations in October 2020, which now has a capacity of 1300 beds.


United Kingdom

The British National Health Service (NHS) took action to set up temporary COVID-19 hospitals nationwide when the first widespread COVID-19 outbreak hit the nation in March 2020. In England, the construction of 7 temporary hospitals were announced in succession between 24 March and 10 April 2020 by the UK government and the NHS, collectively named the
NHS Nightingale Hospitals COVID-19 hospitals in the United Kingdom are temporary hospitals set up in the United Kingdom and overseas territories as part of the response to the COVID-19 pandemic. They principally include the seven NHS England Nightingale Hospitals, NH ...
. These hospitals, collectively providing up to 13700 beds, were planned to house COVID-19 patients with mild conditions, in order to vacate capacity in other NHS hospitals for more critical patients. Most of the 7 hospitals were converted from current exhibition centres: for example, the
NHS Nightingale Hospital London The NHS Nightingale Hospital London was the first of the NHS Nightingale Hospitals, temporary hospitals set up by NHS England for the COVID-19 pandemic. It was housed in the ExCeL London convention centre in East London. The hospital was rapid ...
is located at
ExCeL London ExCeL London (an abbreviation for Exhibition Centre London) is an exhibition centre, international convention centre and former hospital in the Custom House, Newham, Custom House area of London Borough of Newham, Newham, East London. It is sit ...
; while the Birmingham hospital is housed by the
National Exhibition Centre The National Exhibition Centre (NEC) is an exhibition centre located in Marston Green, Solihull, West Midlands, England. It is near junction 6 of the M42 motorway, and is adjacent to Birmingham Airport and Birmingham International railway stati ...
. The London facility was the first to open on 3 April; 6 of the 7 hospitals were opened by 5 May. Only 3 of the 7 hospitals have ever admitted COVID-19 patients. All NHS Nightingale hospitals were “placed on standby” after June 2020, and will be shut down starting from April 2021. The NHS also constructed temporary hospitals in other parts of the UK, in similar fashion as the English NHS Nightingale Hospitals. During April to May 2020,
Scotland Scotland (, ) is a country that is part of the United Kingdom. Covering the northern third of the island of Great Britain, mainland Scotland has a border with England to the southeast and is otherwise surrounded by the Atlantic Ocean to the ...
,
Wales Wales ( cy, Cymru ) is a Countries of the United Kingdom, country that is part of the United Kingdom. It is bordered by England to the Wales–England border, east, the Irish Sea to the north and west, the Celtic Sea to the south west and the ...
, Northern Ireland, Jersey, and Gibraltar all had one or more hospitals opened.


United States

From March 2020, when the COVID-19 pandemic first hit the USA, rapidly rising patient numbers caused US hospitals nationwide to face a critical shortage of beds, manpower, and medical supplies. In response to the bed shortages, the
US Army Corps of Engineers , colors = , anniversaries = 16 June (Organization Day) , battles = , battles_label = Wars , website = , commander1 = ...
announced plans in late-March to construct as many as 341 temporary hospitals across the country. Plans were scaled down when construction began in early April, with 17 existing sites converted into hospitals, providing around 15000 beds. Most of the hospitals were completed and opened in mid to late April. By early May, only 4 of 17 hospitals had treated COVID-19 patients, with none reaching its full capacity. Most of the hospitals have since been put into standby or shut down.


Future directions for infection control in hospitals

The World Health Organisation (WHO) and national pandemic response teams, such as the
UK Health Security Agency The UK Health Security Agency (UKHSA) is a government agency in the United Kingdom, responsible since April 2021 for England-wide public health protection and infectious disease capability, and replacing Public Health England. It is an executiv ...
have suggested regulations to ease and control the infection burden on a national and global scale for preventing future outbreaks of transmissible infections. Some general suggestions are listed as follows: * All healthcare workers in the hospital should remain vigilant of the incoming susceptible patient(s) and personal protective protocols should be taken as needed. * Hospitals need to maintain good communication networks for letting designated clinical centres to receive infected patients and for transporting patients from point to point in an efficient and safe manner. * Healthcare departments of all countries need to plan pre-outbreak protocols to protect the populations with a weak immunity, such as the elderly, the youth and the people with long-term illnesses. * Hospitals need to establish rapid response teams in face of a disease outbreak. * Hospitals should be well-equipped with life supporting machines for severely ill patients, such as pulse oximeters, oxygen and invasive support and other supplies, such as medication and personal protective equipment. * All hospital services should be strategically distributed throughout the country during an infection outbreak, so that essential and emergency medical treatments can be provided on a standard basis.


References

{{Reflist COVID-19 Hospitals Types of hospitals