Costunolide Synthase
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Costunolide synthase () is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with systematic name ''germacra-1(10),4,11(13)-trien-12-oate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating)''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: germacra-1(10),4,11(13)-trien-12-oate + NADPH + H+ + O2 \rightleftharpoons (+)-costunolide + NADP+ + 2 H2O Costunolide synthase is a heme-
thiol In organic chemistry, a thiol (; ), or thiol derivative, is any organosulfur compound of the form , where R represents an alkyl or other organic substituent. The functional group itself is referred to as either a thiol group or a sulfhydryl gro ...
ate protein (P-450).


References


External links

* EC 1.14.13 {{enzyme-stub