''Cosavirus'' is a genus of
viruses
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea.
Since Dmitri Ivanovsky's 1 ...
in the order ''
Picornavirales
''Picornavirales'' is an order of viruses with vertebrate, invertebrate, protist and plant hosts. The name has a dual etymology. First, ''picorna-'' is an acronym for poliovirus, insensitivity to ether, coxsackievirus, orphan virus, rhinovirus, ...
'', in the family ''
Picornaviridae
Picornaviruses are a group of related nonenveloped RNA viruses which infect vertebrates including fish, mammals, and birds. They are viruses that represent a large family of small, positive-sense, single-stranded RNA viruses with a 30 nm i ...
''. Human serve as natural hosts. There are 5 species in this genus.
It is unclear whether cosaviruses are connected to
gastroenteritis
Gastroenteritis, also known as infectious diarrhea and gastro, is an inflammation of the gastrointestinal tract including the stomach and intestine. Symptoms may include diarrhea, vomiting, and abdominal pain. Fever, lack of energy, and dehydra ...
in humans.
Taxonomy
The genus contains the following five species:
* ''
Cosavirus A''
* ''
Cosavirus B''
* ''
Cosavirus C''
* ''
Cosavirus D''
* ''
Cosavirus E''
Structure
Viruses in ''Cosavirus'' are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 7-8kb in length.
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]
Life cycle
Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by ribosomal skipping. The virus exits the host cell by lysis, and viroporins. Human serve as the natural host. Transmission routes are fecal-oral.[
]
References
External links
Viralzone: Cosavirus
ICTV
{{Taxonbar, from=Q18814482
Picornaviridae
Virus genera