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''Corynebacterium glutamicum'' is a
Gram-positive In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall. Gram-positive bacte ...
,
rod-shaped A bacillus (), also called a bacilliform bacterium or often just a rod (when the context makes the sense clear), is a rod-shaped bacterium or archaeon. Bacilli are found in many different taxonomic groups of bacteria. However, the name '' Baci ...
bacterium Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
that is used industrially for large-scale production of
amino acids Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha am ...
. While originally identified in a screen for organisms secreting
L-glutamate Glutamic acid (symbol Glu or E; the ionic form is known as glutamate) is an α-amino acid that is used by almost all living beings in the biosynthesis of proteins. It is a non-essential nutrient for humans, meaning that the human body can syn ...
, mutants of ''C. glutamicum'' have also been identified that produce various other amino acids. Due to its industrial importance, several clones of ''C. glutamicum'' have been sequenced by both industry and academic groups. Furthermore,
small RNA Small RNA (sRNA) are polymeric RNA molecules that are less than 200 nucleotides in length, and are usually non-coding Non-coding DNA (ncDNA) sequences are components of an organism's DNA that do not encode protein sequences. Some non-coding DNA ...
data was obtained by RNA-Seq in ''C. glutamicum'' ATCC 13032. The
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
of this strain has been reconstructed and is available in the form of a genome-scale metabolic model.


See also

*
List of sequenced bacterial genomes This list of sequenced eubacterial genomes contains most of the eubacteria known to have publicly available complete genome sequences. Most of these sequences have been placed in the International Nucleotide Sequence Database Collaboration, a publ ...


References


External links


Genome sequence for ''C. glutamicum''
from
NCBI The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. The ...
.
Type strain of ''Corynebacterium glutamicum'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
{{Taxonbar, from=Q292314 Gram-positive bacteria Corynebacterium