Corrinoid Iron-sulfur Protein
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5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase (, ''acsE (gene)'') is an
enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with systematic name ''5-methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase''. This enzyme catalyses the following
chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: ethyl-Co(III) corrinoid Fe-S protein+ tetrahydrofolate \rightleftharpoons a o(I) corrinoid Fe-S protein+ 5-methyltetrahydrofolate This enzyme catalyses the transfer of a methyl group from the N5 position of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein, containing a corrin ring similar to that in cobalamin.


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