The conformational dynamics data bank (CDDB) is a
database
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spa ...
about
conformational dynamics of
heavy proteins and
protein assemblies. The CDDB is useful when used alongside static structural data to aid research into
protein function. It is also helpful in identifying protein assemblies that are essential to
cell function.
Analysis is carried out by
coarse-grained computation of the structures present in the
electron microscopy data bank (EMDB). This analysis shows
equilibrium thermal fluctuations and
elastic strain energy distributions, which allows for identification of rigid and flexible protein domains. The results also provide information on correlations in
molecular motions which can be used to identify molecular regions that are highly coupled dynamically.
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References
External links
Data bank website
Biological databases
Protein structure
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