Complex partial status epilepticus (CPSE) is one of the non-convulsive forms of

status epilepticus Status epilepticus (SE), or status seizure, is a single seizure lasting more than 5 minutes or 2 or more seizures within a 5-minute period without the person returning to normal between them. Previous definitions used a 30-minute time limit. The s ...

, a rare form of epilepsy defined by its recurrent nature. CPSE is characterized by seizures involving long-lasting

stupor Stupor is the lack of critical mental function and a level of consciousness, in which an affected person is almost entirely unresponsive and responds only to intense stimuli such as pain. The word derives from the Latin '' stupor'' ("numbness, inse ...

, staring and unresponsiveness. Sometimes this is accompanied by motor

automatisms Automatism refers to a set of brief unconscious behaviors. These typically last for several seconds to minutes or sometimes longer, a time during which the subject is unaware of his/her actions. This type of automatic behaviour often occurs in c ...

, such as eye twitching.

Diagnosis

As is the case with other non-convulsive status epilepticus forms, CPSE is dangerously underdiagnosed. This is due to the potentially fatal yet veiled nature of the symptoms. Usually, an electroencephalogram, or EEG, is needed to confirm a neurologist's suspicions. The EEG is also needed to differentiate between absence status epilepticus (which affects the entire brain), and CPSE, which only affects one region.

Treatment

Treatment is in the form of anti-epileptic drugs, such as

barbiturate Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics, and anticonvulsants, but have physical and psychological addiction potential as we ...

benzodiazepine Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, ...

s and

topiramate Topiramate, sold under the brand name Topamax among others, is a carbonic anhydrase inhibitor medication used to treat epilepsy and prevent migraines. It has also been used in alcohol dependence. For epilepsy this includes treatment for gener ...

References

External links

{{DEFAULTSORT:Complex Partial Status Epilepticus Medical emergencies Epilepsy