Collagen disease is a term previously used to describe systemic
autoimmune diseases (e.g.,
rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are invol ...
,
systemic lupus erythematosus, and
systemic sclerosis
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two ...
), but now is thought to be more appropriate for diseases associated with defects in
collagen, which is a component of the connective tissue.
The term "collagen disease" was coined by Dr. Alvin F. Coburn in 1932, on his quest to discover streptococcal infection as the cause for rheumatic fever.
See also
*
Collagenopathy, types II and XI
*
Connective tissue disease
A connective tissue disease (collagenosis) is any disease that has the connective tissues of the body as a target of pathology. Connective tissue is any type of biological tissue with an extensive extracellular matrix that supports, binds togeth ...
References
External links
Collagen diseaseentry in the public domain NCI Dictionary of Cancer Terms
Autosomal dominant disorders
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