Cocoonase is a

trypsin Trypsin is an enzyme in the first section of the small intestine that starts the digestion of protein molecules by cutting these long chains of amino acids into smaller pieces. It is a serine protease from the PA clan superfamily, found in the dig ...

-like

proteolytic Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, ...

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

produced by

silkworm The domestic silk moth (''Bombyx mori''), is an insect from the moth family Bombycidae. It is the closest relative of ''Bombyx mandarina'', the wild silk moth. The silkworm is the larva or caterpillar of a silk moth. It is an economically imp ...

s (of both ''

Bombyx ''Bombyx'' is the genus of true silk moths or mulberry silk moths of the family Bombycidae, also known as silkworms, which are the larvae or caterpillars of silk moths. The genus was erected as a subgenus by Carl Linnaeus in his 10th edition of ...

'' and ''

Antheraea ''Antheraea'' is a moth genus belonging to the family Saturniidae. The genus was erected by Jacob Hübner in 1819. Several species of this genus have caterpillars which produce wild silk of commercial importance. Commonly called "tussar silk", t ...

'' species) as they near the final stages of their

metamorphosis Metamorphosis is a biological process by which an animal physically develops including birth or hatching, involving a conspicuous and relatively abrupt change in the animal's body structure through cell growth and differentiation. Some inse ...

. It is produced by cells in the

proboscis A proboscis () is an elongated appendage from the head of an animal, either a vertebrate or an invertebrate. In invertebrates, the term usually refers to tubular mouthparts used for feeding and sucking. In vertebrates, a proboscis is an elong ...

and exuded onto the galeae. Its function is to weaken the fibers of the cocoon, thereby facilitating the emergence of the adult insect. It was discovered by Carroll Williams.Memorial Minutes on Carroll Williams (FAS) and Aaron Gissen (HMS) and Louis Zetzel (HMS)
, from the

Harvard Gazette Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...

; published March 21, 1996; retrieved November 16, 2011

External links

Cocoonase of ''Bombyx mori''
at

UniProt UniProt is a freely accessible database of protein sequence and functional information, many entries being derived from genome sequencing projects. It contains a large amount of information about the biological function of proteins derived from ...

Cocoonase-assisted protein of ''Bombyx mori''
at

References

Bombycidae Silk {{enzyme-stub