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In the pre-modern
chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...
of
Paracelsus Paracelsus (; ; 1493 – 24 September 1541), born Theophrastus von Hohenheim (full name Philippus Aureolus Theophrastus Bombastus von Hohenheim), was a Swiss physician, alchemist, lay theologian, and philosopher of the German Renaissance. He w ...
, a clyssus, or clissus, was one of the effects, or productions of that art; consisting of the most efficacious
principle A principle is a proposition or value that is a guide for behavior or evaluation. In law, it is a Legal rule, rule that has to be or usually is to be followed. It can be desirably followed, or it can be an inevitable consequence of something, suc ...
s of any body, extracted, purified, and then remixed. Or, a clyssus is when the several constituents of a body are prepared and purified separately, and then combined again. Thus, the five
principle A principle is a proposition or value that is a guide for behavior or evaluation. In law, it is a Legal rule, rule that has to be or usually is to be followed. It can be desirably followed, or it can be an inevitable consequence of something, suc ...
s, reassembled into one body, by long digestion, make a clyssus. So, ''clyssus of antimony'' is produced by
distillation Distillation, or classical distillation, is the process of separation process, separating the components or substances from a liquid mixture by using selective boiling and condensation, usually inside an apparatus known as a still. Dry distilla ...
from
antimony Antimony is a chemical element with the symbol Sb (from la, stibium) and atomic number 51. A lustrous gray metalloid, it is found in nature mainly as the sulfide mineral stibnite (Sb2S3). Antimony compounds have been known since ancient time ...
,
nitre Niter or nitre is the mineral form of potassium nitrate, KNO3. It is a soft, white, highly soluble mineral found primarily in arid climates or cave deposits. Historically, the term ''niter'' was not well differentiated from natron, both of w ...
, and
sulfur Sulfur (or sulphur in British English) is a chemical element with the symbol S and atomic number 16. It is abundant, multivalent and nonmetallic. Under normal conditions, sulfur atoms form cyclic octatomic molecules with a chemical formula ...
mixed together. There is also ''clyssus of vitriol'', which is a spirit drawn by distillation from
vitriol Vitriol is the general chemical name encompassing a class of chemical compound comprising sulfates of certain metalsoriginally, iron or copper. Those mineral substances were distinguished by their color, such as green vitriol for hydrated iron(II ...
dissolved in
vinegar Vinegar is an aqueous solution of acetic acid and trace compounds that may include flavorings. Vinegar typically contains 5–8% acetic acid by volume. Usually, the acetic acid is produced by a double fermentation, converting simple sugars to et ...
; this was used by pre-modern physicians in treating various diseases, and to extract the
tincture A tincture is typically an extract of plant or animal material dissolved in ethanol (ethyl alcohol). Solvent concentrations of 25–60% are common, but may run as high as 90%.Groot Handboek Geneeskrachtige Planten by Geert Verhelst In chemistr ...
s of several vegetables. Clyssus is used among some authors for a kind of ''sapa'', or extract, made with eight parts of the
juice Juice is a drink made from the extraction or Cold-pressed juice, pressing of the natural liquid contained in fruit and vegetables. It can also refer to liquids that are flavored with concentrate or other biological food sources, such as meat ...
of a plant, and one of
sugar Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double ...
, seethed together into the consistency of
honey Honey is a sweet and viscous substance made by several bees, the best-known of which are honey bees. Honey is made and stored to nourish bee colonies. Bees produce honey by gathering and then refining the sugary secretions of plants (primar ...
.


References

{{1728, title=Clyssus History of pharmacy Alchemical substances