Claypool is a surname. Notable people with the surname include:
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Chase Claypool (born 1998), Canadian-born American football player
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Forrest Claypool, American politician
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Horatio C. Claypool, U.S. Congressman
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Harold K. Claypool, U.S. Congressman
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Les Claypool, American bassist, singer
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Philip Claypool
Philip Kennard Claypool (born in Memphis, Tennessee) is an American country music artist. Between 1995 and 1999, he recorded two studio albums for the Curb Records label (1995's ''A Circus Leaving Town'' and 1999's ''Perfect World''), in additio ...
, American country music artist
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Ralph Claypool, American football player
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William Claypool, American racehorse trainer
{{surname, Claypool