Clavaminate synthase (, ''clavaminate synthase 2'', ''clavaminic acid synthase'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:(1)
deoxyamidinoproclavaminate +
2-oxoglutarate + O
2 amidinoproclavaminate +
succinate
Succinic acid () is a dicarboxylic acid with the chemical formula (CH2)2(CO2H)2. The name derives from Latin ''succinum'', meaning amber. In living organisms, succinic acid takes the form of an anion, succinate, which has multiple biological ro ...
+ CO
2
:(2)
proclavaminate + 2-oxoglutarate + O
2 dihydroclavaminate + succinate + CO
2 + H
2O
:(3)
dihydroclavaminate + 2-oxoglutarate + O
2 clavaminate + succinate + CO
2 + H
2O
Clavaminate synthase contains nonheme
iron
Iron () is a chemical element with Symbol (chemistry), symbol Fe (from la, Wikt:ferrum, ferrum) and atomic number 26. It is a metal that belongs to the first transition series and group 8 element, group 8 of the periodic table. It is, Abundanc ...
.
References
External links
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EC 1.14.11