The
enzyme citramalyl-CoA lyase ()
catalyzes
Catalysis () is the process of increasing the rate of a chemical reaction by adding a substance known as a catalyst (). Catalysts are not consumed in the reaction and remain unchanged after it. If the reaction is rapid and the catalyst recyc ...
the
chemical reaction
:(3''S'')-citramalyl-CoA
acetyl-CoA + pyruvate
This enzyme belongs to the family of
lyase
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. ...
s, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The
systematic name of this enzyme class is (3''S'')-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming). Other names in common use include citramalyl coenzyme A lyase, (+)-CMA-CoA lyase, and (3''S'')-citramalyl-CoA pyruvate-lyase. This enzyme participates in
pyruvate metabolism
Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base
A conjugate acid, within the Brønsted–Lowry acid–base theory, is a chemical compoun ...
and
c5-branched dibasic acid metabolism.
References
*
*
EC 4.1.3
Enzymes of unknown structure
{{4.1-enzyme-stub