Cipla Limited (stylized as Cipla) is an Indian multinational
pharmaceutical
A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and ...
company, headquartered in
Mumbai
Mumbai (, ; also known as Bombay — the official name until 1995) is the capital city of the Indian state of Maharashtra and the ''de facto'' financial centre of India. According to the United Nations, as of 2018, Mumbai is the secon ...
. Cipla primarily develops medicines to treat
respiratory disease
Respiratory diseases, or lung diseases, are pathological conditions affecting the organs and tissues that make gas exchange difficult in air-breathing animals. They include conditions of the respiratory tract including the trachea, bronchi, ...
,
cardiovascular disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. CVD includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs include stroke, ...
,
arthritis,
diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level (hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ...
,
depression and many other medical conditions.
Cipla has 47 manufacturing locations across the world and sells its products in 86 countries. It is the third largest drug producer in
India
India, officially the Republic of India ( Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the ...
.
History
In 1935, Cipla was founded by
Khwaja Abdul Hamied as 'The Chemical, Industrial & Pharmaceutical Laboratories
' in Mumbai.
In July 1984, the name of the company was changed to 'Cipla Limited'.
[
In 1985, the US FDA approved the company's bulk drug against HIV and other drugs to treat poor people in the developing world.]
Led by the founder's son Yusuf Hamied, a Cambridge-educated chemist, the company provided generic AIDS and other drugs to treat poor people in the developing world.
In 1995, Cipla launched Deferiprone, the world's first oral iron chelator.[ In 2001, Cipla offered antiretrovirals for HIV treatment at a fractional cost (less than $350 per year per patient).
In 2013 Cipla acquired the South African company Cipla-Medpro, kept it as a subsidiary, and changed its name to Cipla Medpro South Africa Limited.] At the time of the acquisition Cipla-Medpro had been a distribution partner for Cipla and was South Africa's third biggest pharmaceutical company.[ The company had been founded in 2002 and was known as Enaleni Pharmaceuticals Ltd. In 2005, Enaleni bought all the shares of Cipla-Medpro, which had been a joint venture between Cipla and Medpro Pharmaceuticals, a South African generics company, and in 2008 it changed its name to Cipla-Medpro.
In September 2015, Cipla acquired InvaGen Pharmaceuticals and Exelan Pharmaceuticals, two American pharmaceutical companies, for 555 million dollars.
In 2019 Cipla entered ]digital therapeutics Digital therapeutics, a subset of digital health, are evidence-based therapeutic interventions driven by high quality software programs to prevent, manage, or treat a medical disorder or disease. Digital therapeutic companies should publish trial re ...
by partnering with Wellthy Therapeutics in India and Brandmed in South Africa.
Products and services
Cipla sells active pharmaceutical ingredients to other manufacturers as well as pharmaceutical and personal care products, including escitalopram oxalate (anti-depressant), lamivudine, and fluticasone propionate. They are the world's largest manufacturer of antiretroviral drugs.[
In July 2020, the company announced the introduction of ]Gilead Sciences
Gilead Sciences, Inc. () is an American biopharmaceutical company headquartered in Foster City, California, that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, hepatitis C, influenza, and ...
' ''Remdesivir
Remdesivir, sold under the brand name Veklury, Text was copied from this source which is © European Medicines Agency. Reproduction is authorized provided the source is acknowledged. is a broad-spectrum antiviral medication developed by the ...
'' under the brand name CIPREMI in India after reaching a voluntary licensing agreement with parent company and DCGI approval for "restricted emergency use" in COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was identified in Wuhan, China, in December 2019. The disease quickl ...
treatment of critical confirmed patients.
Operations
Cipla has 34 manufacturing units in 8 locations across India and a presence in over 80 countries. Exports accounted for 48% of its revenue for FY 2013–14. Cipla spent 517 crore (5.4% of their revenue) in FY 2013–14 on R&D activities.[ The primary focus areas for R&D were development of new formulations, drug-delivery systems and APIs (active pharmaceutical ingredients). Cipla also cooperates with other enterprises in areas such as consulting, commissioning, engineering, project appraisal, quality control, know-how transfer, support, and plant supply.
As on 31 March 2013, the company had 22,036 employees (out of which 2,455 were women (7.30%) and 23 were employees with disabilities (0.1%)).][ During the FY 2013–14, the company incurred on employee benefit expenses.][
]
Listings and Shareholding
The equity shares of Cipla are listed on the Bombay Stock Exchange
BSE Limited, also known as the Bombay Stock Exchange (BSE), is an Indian stock exchange. It is located on Dalal Street in Mumbai. Established in 1875 by cotton merchant Premchand Roychand, a Jain businessman, it is the oldest stock exchange i ...
, where it is a constituent of the BSE SENSEX index, and the National Stock Exchange of India, where it is a constituent of the CNX Nifty
The NIFTY 50 is a benchmark Indian stock market index that represents the weighted average of 50 of the largest Indian companies listed on the National Stock Exchange. It is one of the two main stock indices used in India, the other being th ...
. Its Global Depository Receipts (GDRs) are listed on the Luxembourg Stock Exchange.[
As of 30 September 2014, the promoter group, Y. K. Hamied and his family, held around 36.80% equity shares in Cipla. Around 148,000 individual shareholders held approx. 18.67% of its shares.] LIC is the largest non-promoter shareholder with approx. 6.45% shareholding in the company by the end of September 2013.
Awards and recognitions
* In 2012, Cipla received the Thomson Reuters India Innovation Award.
* Cipla won Dun & Bradstreet American Express Corporate Awards in 2006.
* In 2007, Forbes
''Forbes'' () is an American business magazine owned by Integrated Whale Media Investments and the Forbes family. Published eight times a year, it features articles on finance, industry, investing, and marketing topics. ''Forbes'' also r ...
included Cipla in the 200 'Best under a billion' list of best small Asian companies.
* In 1980, Cipla won Chemexcil Award for Excellence for exports.
* In 2015, Cipla stood third in the India's Most Reputed Brands (Pharmaceutical) list, in a study conducted by BlueBytes, a leading Media Analytics firm in association with TRA Research, a brand insights organization (both a part of the Comniscient Group).
Criticism
Emergency contraception
In August 2007, Cipla launched an emergency contraception
Emergency contraception (EC) is a birth control measure, used after sexual intercourse to prevent pregnancy.
There are different forms of EC. Emergency contraceptive pills (ECPs), sometimes simply referred to as emergency contraceptives (ECs), ...
drug "i-pill" sold over the counter, which was controversial with regard to its being available without a prescription and the large amount of drug contained per dose.
Generic drugs
In the late 1960s, Cipla began manufacturing a new, patented drug, propranolol, without the permission of the drug's patent holder, Imperial Chemical Industries
Imperial Chemical Industries (ICI) was a British chemical company. It was, for much of its history, the largest manufacturer in Britain.
It was formed by the merger of four leading British chemical companies in 1926.
Its headquarters were at M ...
(ICI), who protested to the Indian government. The CEO of Cipla pressured the government of Indira Gandhi to change India's patent laws to eliminate patents that directly covered drugs, and instead to allow only patents that covered methods to make drugs. so that Cipla could go ahead and produce as many low-priced generic drugs for the poor as possible. Since then Cipla has also produced a low-cost drug to treat HIV, and expanded operations into several developing countries, including African nations, where most HIV and poor patients existed at one time. But the changes made led to criticism of both India's patent laws and Cipla. India reinstated patents on drugs in 2005.[
]
See also
* Pharmaceutical industry in India
* Generic drug
A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire. Because the active ...
* List of pharmaceutical companies
This listing is limited to those independent companies and subsidiaries notable enough to have their own articles in Wikipedia. Both going concerns and defunct firms are included, as well as firms that were part of the pharmaceutical industry ...
References
External links
*
{{Authority control
Biotechnology companies of India
Pharmaceutical companies of India
Pharmaceutical companies established in 1935
NIFTY 50
Biopharmaceutical companies
Indian brands
Indian companies established in 1935
Companies listed on the National Stock Exchange of India
Companies listed on the Bombay Stock Exchange