Cinnamtannin B1
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Cinnamtannin B1 is a
condensed tannin Condensed tannins (proanthocyanidins, polyflavonoid tannins, catechol-type tannins, pyrocatecollic type tannins, non-hydrolyzable tannins or flavolans) are polymers formed by the condensation of flavans. They do not contain sugar residues. They ...
found in ''
Cinnamomum verum ''Cinnamomum verum'', called true cinnamon tree or Ceylon cinnamon tree, is a small evergreen tree belonging to the family Lauraceae, native to Sri Lanka. The inner bark of several other ''Cinnamomum'' species are also used to make cinnamon, but ...
''. It is a type A proanthocyanidin. Cinnamon could have some pharmacological effects in the treatment of type 2 diabetes mellitus and
insulin resistance Insulin resistance (IR) is a pathological condition in which cell (biology), cells fail to respond normally to the hormone insulin. Insulin is a hormone that facilitates the transport of glucose from blood into cells, thereby reducing blood gluco ...
. The plant material used in the study was mostly from Chinese cinnamon (see Chinese cinnamon's medicinal uses). Recent studies in
phytochemistry Phytochemistry is the study of phytochemicals, which are chemicals derived from plants. Phytochemists strive to describe the structures of the large number of secondary metabolites found in plants, the functions of these compounds in human and ...
have indicated that cinnamtannin B1 isolated from ''C.
Verum The tee (⊤, \top in LaTeX) also called down tack (as opposed to the up tack) or verum is a symbol used to represent: * The top element in lattice theory. * The truth value of being true in logic, or a sentence (e.g., formula in propositional ca ...
'' bears possible therapeutic effect on type 2 diabetes, with the exception of the postmenopausal patients studied on ''
Cinnamomum aromaticum ''Cinnamomum cassia'', called Chinese cassia or Chinese cinnamon, is an evergreen tree originating in southern China, and widely cultivated there and elsewhere in South and Southeast Asia (India, Indonesia, Laos, Malaysia, Thailand, and Vietnam) ...
''. Cinnamtannin B1 possesses several phenolic hydroxyl groups and is reported to exhibit antioxidant property, antimicrobial activities, and anti-platelet aggregation that may protect damaged tissues in woundsFujita K, Kuge K, Ozawa N, Sahara S, Zaiki K, Nakaoji K, et al. (2015) Cinnamtannin B-1 Promotes Migration of Mesenchymal Stem Cells and Accelerates Wound Healing in Mice. PLoS ONE 10(12): e0144166.


References

{{Procyanidin Procyanidins Natural phenol trimers