Cilag AG is a

Swiss Swiss may refer to: * the adjectival form of Switzerland * Swiss people Places * Swiss, Missouri * Swiss, North Carolina *Swiss, West Virginia * Swiss, Wisconsin Other uses *Swiss-system tournament, in various games and sports *Swiss Internation ...

pharmaceutical A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and re ...

company. Cilag is a subsidiary of American pharmaceutical giant

Johnson & Johnson Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...

. The company's global marketing activities are operated by

Janssen-Cilag Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company i ...

, a merger with another Johnson & Johnson subsidiary,

Janssen Pharmaceuticals Janssen Pharmaceuticals is a pharmaceutical company headquartered in Beerse, Belgium, and wholly-owned by Johnson & Johnson. It was founded in 1953 by Paul Janssen. In 1961, Janssen Pharmaceuticals was purchased by New Jersey-based American c ...

Company history

In 1933, Swiss chemist

Bernhard Joos Bernhard Joos (18 December 1899 Schaffhausen, Switzerland – 8 June 1990 Paradiso, Switzerland), was the son of Dr. Bernhard Joos and Olga Sturzenegger. He attained a PhD in chemistry at the University of Zurich in 1925, and was an assistant of Pa ...

set up a small research laboratory in

Schaffhausen Schaffhausen (; gsw, Schafuuse; french: Schaffhouse; it, Sciaffusa; rm, Schaffusa; en, Shaffhouse) is a list of towns in Switzerland, town with historic roots, a municipalities of Switzerland, municipality in northern Switzerland, and the ...

Switzerland ). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel ...

. This set the basis for the founding of ''Chemische Industrie-Labor AG'' (Chemical Industry Laboratory AG or Cilag) on 12 May 1936. The first president of Cilag's administrative board was Carl Naegeli, a well-known professor at the Chemical Institute of the

University of Zurich The University of Zürich (UZH, german: Universität Zürich) is a public research university located in the city of Zürich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 f ...

. After the death of Naegeli in 1942, Joos himself then took over the managing role until he left the company in 1949. In 1959, Cilag joined the

family of companies. In the early 1990s, the marketing organizations of Cilag and

were joined to form

. The non-marketing activities of both companies still operate under their original name. Cilag continues to have operations under the Cilag name in Switzerland, ranging from research and development through manufacturing and international services. In August 2014 Cilag acquired Covagen a biopharmaceutical company which specialises in the development of multi-specific protein based therapeutics. As part of the acquisition Cilag will gain access to Covagen’s lead drug candidate, COVA 322, a bi-specific anti-tumor necrosis factor (TNF)-alpha/anti-interleukin (IL)-17A FynomAb, is in a Phase Ib study for

psoriasis Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by raised areas of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete ...

Product history

Joos' first discovery was pyridazil, an azo dyestuff derived from

pyridine Pyridine is a basic heterocyclic organic compound with the chemical formula . It is structurally related to benzene, with one methine group replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a d ...

, which is an

analgesic An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It ...

for the

urinary tract The urinary system, also known as the urinary tract or renal system, consists of the kidneys, ureters, bladder, and the urethra. The purpose of the urinary system is to eliminate waste from the body, regulate blood volume and blood pressure, con ...

.Zelenitsky SA, Zhanel GG., Phenazopyridine in urinary tract infections, Ann Pharmacother. 1996 Jul-Aug;30(7-8):866-8 By 1952 Joos had discovered seven new chemical compounds and developed them into new products. The company's research and development record covers discoveries and developments in the fields of

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all par ...

women's health Women's health differs from that of men in many unique ways. Women's health is an example of population health, where health is defined by the World Health Organization as "a state of complete physical, mental and social well-being and not mer ...

dermatology Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical ...

anti-infectives An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dis ...

and

immunology Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there ...

References

External links

Cilag AG
{{Authority control Swiss companies established in 1936 Pharmaceutical companies established in 1936 Pharmaceutical companies of Switzerland Johnson & Johnson subsidiaries 1959 mergers and acquisitions

Company history

Product history

See also

References

External links