Christos Ouzounis
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Christos A. Ouzounis is a
computational biologist Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has fo ...
, a director of research at the CERTH, and Professor of Bioinformatics at
Aristotle University Aristotle (; grc-gre, Ἀριστοτέλης ''Aristotélēs'', ; 384–322 BC) was a Greek philosopher and polymath during the Classical period in Ancient Greece. Taught by Plato, he was the founder of the Peripatetic school of phi ...
in
Thessaloniki Thessaloniki (; el, Θεσσαλονίκη, , also known as Thessalonica (), Saloniki, or Salonica (), is the second-largest city in Greece, with over one million inhabitants in its Thessaloniki metropolitan area, metropolitan area, and the capi ...
.


Education

Ouzounis received his undergraduate degree (B.Sc.) in Biological Sciences from the
Aristotle University of Thessaloniki Aristotle (; grc-gre, Ἀριστοτέλης ''Aristotélēs'', ; 384–322 BC) was a Greek philosopher and polymath during the Classical period in Ancient Greece. Taught by Plato, he was the founder of the Peripatetic school of phil ...
(AUTH) in 1987. He then received an M.Sc. in Biological Computation from the
University of York , mottoeng = On the threshold of wisdom , established = , type = Public research university , endowment = £8.0 million , budget = £403.6 million , chancellor = Heather Melville , vice_chancellor = Charlie Jeffery , students ...
in 1988 and went on to perform doctoral work with Chris Sander at the
European Molecular Biology Laboratory The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 27 member states, two prospect states, and one associate member state. EMBL was created in 1974 and ...
in
Heidelberg Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914 ...
,
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
receiving his
PhD PHD or PhD may refer to: * Doctor of Philosophy (PhD), an academic qualification Entertainment * '' PhD: Phantasy Degree'', a Korean comic series * ''Piled Higher and Deeper'', a web comic * Ph.D. (band), a 1980s British group ** Ph.D. (Ph.D. albu ...
from the
University of York , mottoeng = On the threshold of wisdom , established = , type = Public research university , endowment = £8.0 million , budget = £403.6 million , chancellor = Heather Melville , vice_chancellor = Charlie Jeffery , students ...
in 1993.


Career and research

After his PhD, Ouzounis was a Human Frontiers Science Program (HFSP) Postdoctoral fellow at
SRI International SRI International (SRI) is an American nonprofit scientific research institute and organization headquartered in Menlo Park, California. The trustees of Stanford University established SRI in 1946 as a center of innovation to support economic d ...
,
Menlo Park, California Menlo Park is a city at the eastern edge of San Mateo County within the San Francisco Bay Area of California in the United States. It is bordered by San Francisco Bay on the north and east; East Palo Alto, Palo Alto, and Stanford to the south; ...
. Ouzounis started his own laboratory, researching computational genomics, at the
European Molecular Biology Laboratory The European Molecular Biology Laboratory (EMBL) is an intergovernmental organization dedicated to molecular biology research and is supported by 27 member states, two prospect states, and one associate member state. EMBL was created in 1974 and ...
,
European Bioinformatics Institute The European Bioinformatics Institute (EMBL-EBI) is an Intergovernmental Organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Well ...
(EMBL-EBI) in 1996. He then moved his laboratory to
King's College London King's College London (informally King's or KCL) is a public research university located in London, England. King's was established by royal charter in 1829 under the patronage of King George IV and the Duke of Wellington. In 1836, King's ...
(KCL), as a Professor, Chair and Director of the KCL Centre for Bioinformatics in 2007. Following the restructuring at King's in 2009/2010, he returned to
Greece Greece,, or , romanized: ', officially the Hellenic Republic, is a country in Southeast Europe. It is situated on the southern tip of the Balkans, and is located at the crossroads of Europe, Asia, and Africa. Greece shares land borders with ...
, joining CPERI at CERTH in
Thessaloniki Thessaloniki (; el, Θεσσαλονίκη, , also known as Thessalonica (), Saloniki, or Salonica (), is the second-largest city in Greece, with over one million inhabitants in its Thessaloniki metropolitan area, metropolitan area, and the capi ...
. In 2020 he was appointed as Professor of Bioinformatics at AUTH. His research interests include genome structure, function and evolution, evolution of protein function, evolution of genetic information-processing systems, theory and applications of biological sequence comparison, data and knowledge representation for genomics, unsupervised machine learning in very large datasets, biologically-inspired hardware & software engineering (unpublished works), synthetic biology, exobiology, and science communication. Some of his best known contributions in the field of computational genomics include automated sequence annotation, the discovery of genomic context methods, the inference of metabolic pathways from genome sequences, the development of methods for large-scale clustering of sequence similarities, the definition of the
Last Universal Common Ancestor The last universal common ancestor (LUCA) is the most recent population from which all organisms now living on Earth share common descent—the most recent common ancestor of all current life on Earth. This includes all cellular organisms; t ...

LUCA
jointly with Nikos Kyrpides, and the quantification of horizontal gene transfer patterns across the "net of life". He also maintains a strong interest in the development of
computational biology Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has fo ...
as an exemplary paradigm in the history of contemporary science, emanating from his first-hand experience that saw bioinformatics grow during the 1990s. He cites as mentors his late father Andreas Ouzounis†, Kostas Kastritsis†, Chris Sander, Antoine Danchin and
Carl Woese Carl Richard Woese (; July 15, 1928 – December 30, 2012) was an American microbiologist and biophysicist. Woese is famous for defining the Archaea (a new domain of life) in 1977 through a pioneering phylogenetic taxonomy of 16S ribosomal RNA, ...
†. His former PhD students include David Kreil (2001), Anton Enright (2002) JM Peregrin-Alvarez (2003), Victor Kunin (2004) Nikos Darzentas (2005) and Ignat Drozdov (2010).


Awards and honours

Ouzounis is associate editor for the journal ''
PLOS Computational Biology ''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computational B ...
'' (since 2007). He is also an associate editor for the journal ''BioSystems'' and Honorary Editor for the journal ''
Bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
''. He is a founding officer of the
International Society for Computational Biology The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Mole ...
(ISCB), th
Mikrobiokosmos
initiative (Greece), the Hellenic Society for Computational Biology & Bioinformatics an
Hellenic Bioinformatics
He is an active member of th
MetaSUB
consortium and a board member o
Elixir-Europe
He was a visiting professor at the
University of Toronto The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution ...
(2011-2014). He is also a committed adventurer/photographer and a trained RYA windsurfing instructor / amateur windsurfing coach.


References

{{DEFAULTSORT:Ouzounis, Christos Living people Computational biologists Greek bioinformaticians Aristotle University of Thessaloniki alumni Alumni of the University of York Greek expatriates in the United Kingdom Academic journal editors 1965 births