Chloe Orkin
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Chloe Meave Orkin is a British physician and Professor of
HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
medicine at
Queen Mary University of London , mottoeng = With united powers , established = 1785 – The London Hospital Medical College1843 – St Bartholomew's Hospital Medical College1882 – Westfield College1887 – East London College/Queen Mary College , type = Public researc ...
. She works as a consultant at the
Royal London Hospital The Royal London Hospital is a large teaching hospital in Whitechapel in the London Borough of Tower Hamlets. It is part of Barts Health NHS Trust. It provides district general hospital services for the City of London and Tower Hamlets and spe ...
,
Barts Health NHS Trust Barts Health NHS Trust is an NHS trust based in London, England. Established in 2012, it runs five hospitals throughout the City of London and East London, and is one of the largest NHS trusts in England. History The trust was established on ...
. She is an internationally renowned expert in HIV therapeutics and led the first phase III clinical trial of injectable
anti-retroviral The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple ...
s. She is immediate past Chair of the
British HIV Association The British HIV Association (BHIVA) is an organisation of healthcare professionals interested in the treatment and care of people with HIV. The current BHIVA Chair is Dr Laura Waters. The aims of BHIVA are, to advance: * Promotion of good prac ...
, where she championed the ''Undetectable=Untransmittable'' (U=U) campaign within the United Kingdom. She is president elect of the
Medical Women's Federation The Medical Women's Federation is the largest UK body of women doctors. The organisation is dedicated to the advancement of the personal and professional development of women in medicine and to improving the health of women and their families i ...
. Orkin is gay and was on the Top 100 Lesbian influencer lists in both the UK and in the US in 2020. She considers herself a medical activist and much of her work focuses on inequalities in healthcare and in Medicine.


Early life and education

Orkin was born in
Johannesburg, South Africa Johannesburg ( , , ; Zulu and xh, eGoli ), colloquially known as Jozi, Joburg, or "The City of Gold", is the largest city in South Africa, classified as a megacity, and is one of the 100 largest urban areas in the world. According to Demo ...
. She obtained her medical degree in 1995 from the
University of the Witwatersrand The University of the Witwatersrand, Johannesburg (), is a multi-campus South African Public university, public research university situated in the northern areas of central Johannesburg. It is more commonly known as Wits University or Wits ( o ...
and was the prize student in virology and microbiology. She began her clinical training at
Chris Hani Baragwanath Hospital Chris Hani Baragwanath Hospital is a hospital in Johannesburg, South Africa, it is the largest hospital in Africa and third largest hospital in the world. It has 6,760 staff members, 3,400 beds and occupies . The hospital is located in the Sow ...
,
Soweto Soweto () is a township of the City of Johannesburg Metropolitan Municipality in Gauteng, South Africa, bordering the city's mining belt in the south. Its name is an English syllabic abbreviation for ''South Western Townships''. Formerly a s ...
in the 1990s. At the time, between 30 and 40% of medical inpatients were infected with
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
and Orkin herself, lost close friends to
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual m ...
. She moved to the United Kingdom. In 1998, she completed her specialist training in
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
and
Genitourinary Medicine Reproductive medicine is a branch of medicine concerning the male and female reproductive systems. It encompasses a variety of reproductive conditions, their prevention and assessment, as well as their subsequent treatment and prognosis. Reprodu ...
at
Chelsea and Westminster Hospital Chelsea and Westminster Hospital is a 430-bed teaching hospital located in Chelsea, London. Although the hospital has been at its present site since only 1993, the hospital has a rich history in that it serves as the new site for the Westminste ...
. Towards the end of her specialist training, Orkin moved to
Botswana Botswana (, ), officially the Republic of Botswana ( tn, Lefatshe la Botswana, label=Setswana, ), is a landlocked country in Southern Africa. Botswana is topographically flat, with approximately 70 percent of its territory being the Kalahar ...
together with nurse colleague and partner Flick Thorley to establish an
HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
treatment programme in
Francistown Francistown is the second largest city in Botswana, with a population of about 103,417 and 147,122 inhabitants for its agglomeration at the 2022 census. and often described as the "''Capital of the North''" or as the natives would have it “''T ...
as part of the government anti-retroviral roll-out. In 2006, Orkin completed a MSc in Infectious Diseases from The
London School of Hygiene & Tropical Medicine The London School of Hygiene and Tropical Medicine (LSHTM) is a public research university in Bloomsbury, central London, and a member institution of the University of London that specialises in public health and tropical medicine. The inst ...
.


Research and career

At the age of 29, Orkin was appointed as Consultant physician at
Barts Health NHS Trust Barts Health NHS Trust is an NHS trust based in London, England. Established in 2012, it runs five hospitals throughout the City of London and East London, and is one of the largest NHS trusts in England. History The trust was established on ...
. Her specialist interests are the development of novel antiretroviral therapies, blood-borne virus testing and health inequalities. In 2013, she led the Test Me East HIV testing campaign which was supported by
David Furnish David James Furnish (born 25 October 1962) is a Canadian filmmaker and former advertising executive. He is married to English singer, pianist and composer Sir Elton John. Early life and education David Furnish was born in Toronto, Ontario, th ...
, Sir
Elton John Sir Elton Hercules John (born Reginald Kenneth Dwight; 25 March 1947) is a British singer, pianist and composer. Commonly nicknamed the "Rocket Man" after his 1972 hit single of the same name, John has led a commercially successful career a ...
and
Sadie Frost Sadie Liza Frost (née Vaughan; born 19 June 1965) is an English actress, producer and fashion designer, who ran fashion label Frost French (until its closure in 2011) and a film production company (Blonde to Black Pictures). Early life Frost ...
and covered by CNN, Channel 4 and ITV news. In 2015, she spearheaded ‘''Going Viral’'', a week-long campaign to raise awareness of blood-borne viruses. The week-long novel campaign offered
HIV The human immunodeficiency viruses (HIV) are two species of ''Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune ...
,
Hepatitis B Hepatitis B is an infectious disease caused by the ''Hepatitis B virus'' (HBV) that affects the liver; it is a type of viral hepatitis. It can cause both acute and chronic infection. Many people have no symptoms during an initial infection. Fo ...
and
Hepatitis C Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, a ...
testing in emergency departments around the United Kingdom utilising an opt-out testing strategy. The campaign was widely covered in the media and supported by several high profile celebrities, including actor Richard Wilson and DJ
Tim Westwood Timothy Westwood (born 3 October 1957) is a British DJ and presenter. He is often referred to by other DJs and artists appearing on his shows simply as Westwood. He was described by ''The Guardian'' in 2022 as "a veteran of the hip-hop scene ...
. She led the first ever phase III clinical trial into the use of injectable
anti-retroviral The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple ...
s. After appearing on
ITV News ITV News is the branding of news programmes on the British television network ITV. ITV has a long tradition of television news. Independent Television News (ITN) was founded to provide news bulletins for the network in 1955, and has since conti ...
to discuss the treatment, she was trolled on social media where many misogynistic and homophobic comments were made about her appearance and sexual identity. This experience led her to take action on gender and sexuality-based discrimination. Shortly after she stood for election and was elected Vice President of the
Medical Women's Federation The Medical Women's Federation is the largest UK body of women doctors. The organisation is dedicated to the advancement of the personal and professional development of women in medicine and to improving the health of women and their families i ...
in 2019. Orkin has also served as Chair of the
British HIV Association The British HIV Association (BHIVA) is an organisation of healthcare professionals interested in the treatment and care of people with HIV. The current BHIVA Chair is Dr Laura Waters. The aims of BHIVA are, to advance: * Promotion of good prac ...
from 2017-2019 and is on the Governing Council for the
International AIDS Society The International AIDS Society (IAS) is the world's largest association of HIV/AIDS professionals, with 11,600 members from over 170 countries , including clinicians, people living with HIV, service providers, policy makers and others. It aims to r ...
. In 2018, Orkin and the
British HIV Association The British HIV Association (BHIVA) is an organisation of healthcare professionals interested in the treatment and care of people with HIV. The current BHIVA Chair is Dr Laura Waters. The aims of BHIVA are, to advance: * Promotion of good prac ...
announced their commitment to the ''Undetectable=Untransmittable'' (U=U) campaign. During the first wave of
COVID-19 pandemic in the United Kingdom The COVID-19 pandemic in the United Kingdom is a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the United Kingdom, it has resulted in confir ...
, she led on safe delivery of COVID-19 treatment trials at the 5 Barts Health NHS Trust hospitals including NHS Nightingale London (the first non-hospital, non-military research delivery). Since then she has led the team that created a new clinical trial centre in a community library to deliver a large SARS CoV2 vaccine trials and was appointed as its clinical director. She has also led research into poor health outcomes in ethnically diverse people and on gender disparities in women's academic careers. She is lead investigator for the first COVID-19 vaccine trial in pregnant women.


Selected publications

HIV Anti-retroviral Therapy: * * * * * * COVID-19 Equality Research: * * Blood-borne Virus Testing in UK Emergency Department: *


Awards and honours

Orkin is a Fellow of the
Royal College of Physicians The Royal College of Physicians (RCP) is a British professional membership body dedicated to improving the practice of medicine, chiefly through the accreditation of physicians by examination. Founded by royal charter from King Henry VIII in 1 ...

FRCP
.


Personal life

Orkin is
lesbian A lesbian is a Homosexuality, homosexual woman.Zimmerman, p. 453. The word is also used for women in relation to their sexual identity or sexual behavior, regardless of sexual orientation, or as an adjective to characterize or associate n ...
. She lives in London with her wife Flick Thorley, who was a highly regarded HIV specialist nurse at
Chelsea and Westminster hospital Chelsea and Westminster Hospital is a 430-bed teaching hospital located in Chelsea, London. Although the hospital has been at its present site since only 1993, the hospital has a rich history in that it serves as the new site for the Westminste ...
and Charge Nurse at the London Lighthouse. They share a home with their three dogs and two cats.


References

{{DEFAULTSORT:Orkin, Chloe Living people Year of birth missing (living people) British women medical doctors British LGBT scientists LGBT physicians People from Johannesburg University of the Witwatersrand alumni Academics of Queen Mary University of London 21st-century LGBT people