Chinedum Peace Babalola
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Chinedum Peace Babalola (née Anyabuike) , is a
Nigerian Nigerians or the Nigerian people are citizens of Nigeria or people with ancestry from Nigeria. The name Nigeria was taken from the Niger River running through the country. This name was allegedly coined in the late 19th century by British jour ...
Professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...
of
Pharmaceutical chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and developme ...
and
Pharmacokinetics Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered ...
. She is the first female Professor of Pharmacy in the
University of Ibadan The University of Ibadan (UI) is a public research university in Ibadan, Nigeria. The university was founded in 1948 as University College Ibadan, one of many colleges within the University of London. It became an independent university in 196 ...
, FAS and FAAS and the second female Nigerian FAAS. She is the incumbent
Vice Chancellor A chancellor is a leader of a college or university, usually either the executive or ceremonial head of the university or of a university campus within a university system. In most Commonwealth and former Commonwealth nations, the chancellor is ...
of
Chrisland University Chrisland University is located in Abeokuta, Ogun State, Nigeria. It was founded in 2015 and is accredited by the National Universities Commission. History On September 17, 2015, the Federal Republic of Nigeria's National Universities Comm ...
, Nigeria.


Background


Education

Chinedum obtained a
Bachelor of Pharmacy A Bachelor of Pharmacy (abbreviated B Pharm or PharmB or BS Pharm) is a graduate academic degree in the field of pharmacy. In many countries, this degree is a prerequisite for registration to practice as a pharmacist. Since both PharmB and Phar ...
(B.Pharm.) degree in 1983,
Master of Science A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to ...
in
Pharmaceutical Chemistry Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and developme ...
in 1987 and a
Doctor of Philosophy A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common Academic degree, degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields ...
in Pharmaceutical Chemistry (
Pharmacokinetics Pharmacokinetics (from Ancient Greek ''pharmakon'' "drug" and ''kinetikos'' "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered ...
option) in 1997 from the University of Ife, now
Obafemi Awolowo University Obafemi Awolowo University (OAU) is a federal government-owned university that is located in the ancient city of Ile-Ife, Osun State, Nigeria. The university was founded in 1961 and classes commenced in October 1962 as the University of Ife ...
. She won the World Bank/NUC scholarship for staff training and completed her pre-doctoral fellowship at the
University of British Columbia The University of British Columbia (UBC) is a public university, public research university with campuses near Vancouver and in Kelowna, British Columbia. Established in 1908, it is British Columbia's oldest university. The university ranks a ...
between 1994 and 1995. In 2012, Chinedum obtained a postgraduate Diploma in Industrial Pharmacy Advanced training (IPAT) jointly issued b
Kilimanjaro School of Pharmacy, Tanzania
and
Purdue University Purdue University is a public land-grant research university in West Lafayette, Indiana, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and money ...
, USA.


Career

Babalola started her academic career as a Junior Trainee/ Graduate Assistant in the Obafemi Awolowo University in 1985. In 1994, she moved to the
University of British Columbia The University of British Columbia (UBC) is a public university, public research university with campuses near Vancouver and in Kelowna, British Columbia. Established in 1908, it is British Columbia's oldest university. The university ranks a ...
to complete a pre-doctoral fellowship. She rose to Lecturer I in the Department of Pharmaceutical Chemistry Obafemi Awolowo University before joining the University of Ibadan as a Senior Lecturer in 1998. Babalola became the University of Ibadan's first female Professor of Pharmacy in October 2006. Prof Babalola is a seasoned university administrator. Prior to her appointment as the Vice Chancellor of Chrisland University, she served as the first female Dean of the Faculty of Pharmacy University of Ibadan (2013-2017), and as an adjunct Professor in the Department of Pharmaceutical Chemistry, Faculty of Pharmacy,
Olabisi Onabanjo University Olabisi Onabanjo University, Ago-Iwoye is a state owned and operated university located in Ago-Iwoye, Ogun State, Nigeria. The university was founded on 7 July 1982 as Ogun State University (OSU) and was renamed Olabisi Onabanjo University on 2 ...
. She was a two-term Director of General Studies (2005 - 2010) University of Ibadan. She is the first pharmacist to be appointed as a specialist adviser and consultant in a Nigerian hospital –
University College Hospital University College Hospital (UCH) is a teaching hospital in the Fitzrovia area of the London Borough of Camden, England. The hospital, which was founded as the North London Hospital in 1834, is closely associated with University College London ...
(UCH), Ibadan.


Research Interest and career

Prof, Babalola's research has been focused on ethics of human research,
pharmacogenetics Pharmacogenomics is the study of the role of the genome in drug response. Its name ('' pharmaco-'' + ''genomics'') reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects the ...
, clinical trials, drug interaction PK/PD, and non-communicable disease (
Sickle Cell Disease Sickle cell disease (SCD) is a group of blood disorders typically inherited from a person's parents. The most common type is known as sickle cell anaemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blo ...
and
Cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
). She developed a novel
High-performance liquid chromatography High-performance liquid chromatography (HPLC), formerly referred to as high-pressure liquid chromatography, is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It relies on pumps to pa ...
method for the analysis of
quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cr ...
in
biometrics Biometrics are body measurements and calculations related to human characteristics. Biometric authentication (or realistic authentication) is used in computer science as a form of identification and access control. It is also used to identify in ...
. This novel method quinine analysis led to the elucidation of the pharmacokinetics of quinine in Africans and formed the basis of dose optimization in
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
patents. Her feasibility studies on drug interactions and
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
suggest a decrease in bioavailability and bacterial activity of certain
antibiotics An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention o ...
when combined with some anti-malaria drugs. She is one of the scientists that reported the first pharmacogenetic study in healthy and sickle cell patients in Nigerians with proguanil as a probe. The report suggested that some Nigerians are carriers of mutant
CYP2C19 Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme protein. It is a member of the CYP2C subfamily of the cytochrome P450 mixed-function oxidase system. This subfamily includes enzymes that catalyze metabolism of xenobiotics, including some p ...
genes and poor drug metabolizers. From 2002 till date, she has been an adjunct Researcher at th
Institute of Advanced Medical Research and Training
(IAMRAT) under Genetic & Bioethics Research Unit; College of Medicine, University of Ibadan. A unit she also headed from 2010–2012. Prof Babalola is a recipient of several fellowships, awards and grants. In 2011, she won the
MacArthur Foundation The John D. and Catherine T. MacArthur Foundation is a private foundation that makes grants and impact investments to support non-profit organizations in approximately 50 countries around the world. It has an endowment of $7.0 billion and p ...
Grant worth $950,000 (2012) for Higher Education Higher Education, with which she set up of th
Centre for Drug Discovery Development and Production
(CDDDP), in the University of Ibadan. Currently, she is the Principal Investigator, on th
USAID
sponsore
USP
PQM+ project on promoting Quality of Medicines in LMIC in CDDDP, UI core-flex (a cooperative agreement - $160M Global). Since she became a professor, she has supervised hundreds of undergraduate students and over 30 postgraduate students (PGD, MSC, M. Phil &PhD). She has over 150 scholarly articles in reputable academic journal as well as books, books chapter, conference abstracts and monograph.


Awards and honours

African Union Kwame Nkrumah Regional Award/Prize for Scientific Excellence at
African Union The African Union (AU) is a continental union consisting of 55 member states located on the continent of Africa. The AU was announced in the Sirte Declaration in Sirte, Libya, on 9 September 1999, calling for the establishment of the Africa ...
Addis Ababa, Ethiopia ($20,000), 2019. Fellow, Nigeria Academy of Pharmacy (NAPharm), 2015 Fellow, West African Postgraduate College of Pharmacists (FPCPharam), 2014 Fellow, African Academy of Science (
AAS
, 2013 Fellow,
Pharmaceutical Society of Nigeria Pharmaceutical Society of Nigeria (PSN) is a professional body for practicing pharmacists in Nigeria and was established in to instill discipline and maintaining professional ethics among members of the organization. The first president of the asso ...
(
PSN
, 2012 Fellow,
Nigerian Academy of science The Nigerian Academy of Science is the official science academy of Nigeria. The academy of science was established on 18 January 1977, as an association of Nigeria's foremost scientists, but incorporated in 1986. It is the apex scientific organ ...

FAS
, 2011 Member
Institute of Public Analyst of Nigeria
(MIPAN) Registered Pharmacist, Nigeria, 1984.


Selected scholarly articles

Below are selected peer-reviewed scholarly publications by Professor Chinedum. * Adehin A, Igbinoba SI, Soyinka JO, Onyeji CO, Babalola CP (2019
Pharmacokinetics of quinine in healthy Nigerian subjects and in patients with uncomplicated malaria: analysis of data using a population approach”
Current Therapeutics Research 91, 33-38 * Oluwasanu MM, Atara N, Balogun W, Awolude O, Kotila O, Aniagwu T, Adejumo P, Oyedele OO, Ogun M, Arinola G, Babalola CP, Olopade CS, Olopade OI and Ojengbede O (2019
Causes and remedies for low research productivity among postgraduate scholars and early career researchers on non-communicable diseases in Nigeria
BMC Research Notes 12:403, 2019 doi:10.1186/s13104-019-4458-y * Nwogu JN, Babalola CP, Ngene SO, Taiwo BO, Berzins B, Ghandhi M (2019
Willingness to Donate Hair Samples for Research Among People Living with HIV/AIDS Attending a Tertiary Health Facility in Ibadan, Nigeria
Aids Research and Human Retroviruses 35 (7) Published Online: 26 June 2019 doi:10.1089/aid.2018.0242 * Kotila OA, Fawole OI, Olopade OI, Ayede AI, Falusi AG, Babalola CP (2019
N-acetyltransferase 2 enzyme genotype–phenotype discordances in both HIV-negative and HIV-positive Nigerians Pharmacogenetics and Genomics
29 (5), 106–113, 2019 DOI: doi:10.1097/FPC.0000000000000373 * Adejumo OE, Kotila TR, Falusi AG, Silva BO, Nwogu JN, Fasinu PS, Babalola CP (2016) Phenotyping and genotyping of CYP2C19 using comparative metabolism of proguanil in sickle-cell disease patients and healthy controls in Nigeria. Pharmacology Research & Perspectives, 4(5): e00252. doi:10.1002/prp2.252 * Ong CT; et al. (2005). Penetration, intracellular accumulation and efflux of tigecycline in human polymorphonuclear neutrophils (PMNs). ''Journal of Antimicrobial Chemotherapy'' 56:498-501. * Babalola CP; et al. (2013) Toxicological Effect of SubTherapeutic, Therapeutic and Overdose regimens of Halofantrine Hydrochloride on Male Albino Rats. ''Pharmacologia'' 4 (3): 180–185, 2013 *Babalola, CP. ; et al. (2010). Cytochrome P450 CYP2C19 genotypes in sickle cell disease patients and normal controls. ''Journal of Clinical Pharmacy and Therapeutics''. 35:471-477 *Babalola CP; et al. (2009) Effect of fluconazole on the pharmacokinetics of halofantrine in healthy volunteers. ''Journal of Clinical Pharmacy and Therapeutics''. 34:677-682 *Maglio D et al. (2005). Pharmacodynamic profile of ertapenem against ''Klebsiella pneumoniae'' and ''Escherichia coli'' in a murine thigh model. ''Journal of Antimicrobial Agents and Chemotherapy'' 49(1):276-280. *Babalola CP; et al. (2002). Effect of proguanil interaction on bioavailability of cloxacillin. ''Journal of Clinical Pharmacy and Therapeutics'', 27: 461-464 *Babalola CP; et al. (2004) Synergistic activity of vancomycin and teicoplanin alone and in combination with streptomycin against Enterococci faecalis with various vancomycin susceptibilities. ''International Journal of Antimicrobial Agents'' 23: 343-348 *Babalola CP; et al. (2004). Comparative bioavailability study of a new quinine suppository and oral quinine in healthy volunteers. ''Tropical Journal of Pharmaceutical Research''. 3(1): 291-297 *Babalola CP; et al. (2004) Adjunctive efficacy of G-CSF on treatment of Pseudomonas aeruginosa pneumonia in neutropenic and non-neutropenic hosts. ''Journal of Antimicrobial Chemotherapy'' 53(6):1098-1100. *Babalola CP; et al. (2004) Bioavailability and bioequivalence (BA/BE) assessment. ''Towards Better Quality Assurance of Drugs in the 3rd ..., 2004 Pg 79'' *Babalola CP; et al. (2006) Analysis of the antimalarial drug halofantrine and its major metabolite N-desbutylhalofantrine in human plasma by high performance liquid chromatography- Journal of pharmaceutical and biomedical analysis, 2006 Cited by 10 Related articles All 6 versions *Babalola CP; et al. (2012) Herbal clinical trials—historical development and application in the 21st Century- Pharmacologia, 2012 cited by 10 related articles *Babalola CP; et al.( 2003) Liquid chromatographic determination of pyronaridine in human plasma and oral dosage form- Journal of Chromatography B, cited by 16 related articles all 6 versions
Babalola CP; et al. (2011) Medical Herbalism and Herbal Clinical Research: A Global Perspective.
*Babalola CP; et al. (2002) Polymorphic oxidative metabolism of proguanil in a Nigerian population - European Journal of Clinical Pharmacology, cited by 19 related articles all 9 versions *Babalola CP; et al. (2011) Evaluation of prescription pattern in Osun state (Southwest) Nigeria - Journal of Public Health and Epidemiology, cited by 39 related articles all 4 version


References


External links


Chinedum Peace Babalola
{{DEFAULTSORT:Babalola, Chinedum Peace Living people Nigerian women academics Obafemi Awolowo University alumni Igbo academics Academic staff of the University of Ibadan Nigerian pharmacists University of British Columbia alumni Women pharmacists Year of birth missing (living people) Fellows of the African Academy of Sciences