History
Charles River was founded in 1947 by Henry Foster, a young veterinarian who purchased one thousand rat cages from a Virginia farm and set up a one-man laboratory in Boston, overlooking the Charles River. In an effort to fulfil the regional need for laboratory animal models, he bred, fed, and cared for the animals and personally delivered them to local researchers. In 1955, the company's headquarters were relocated to their current home in Wilmington, Massachusetts. The organization became an international entity in 1966 with the opening of a new animal production facility in France. The first commercial, comprehensive genetic monitoring program was implemented by Charles River in 1981. Three years later, they were acquired by Bausch & Lomb. During this time, Henry and Jim Foster are still in charge of the company. In 1988, the organization started to expand their portfolio to include the creation of transgenic mice and rats. In the 1990s, Charles River expanded their portfolio further. They purchased Specific Pathogen Antigen Free Avian Services (SPAFAS) and serologic diagnostic services Merck, Sharp, and Dohme in 1992 and started offering ''in vitro'' endotoxin testing two years later. Between 1996 and 2000, the company acquired Endosafe, Inc., was bought back from Bausch & Lomb by Jim Foster, acquired Sierra Biomedical, expanded its portfolio to offer biopharmaceutical services, and went public on the New York Stock Exchange. Charles River launched the Humane Care Imperative in 2002, designed to raise awareness and train their employees on the importance of animal welfare. The same year, they were named "Company of the Year" by The Boston Globe. The company then introduced preconditioning services in 2005 to provide their customers with study-ready animals. In 2008, Charles River signed a ten-year contract to partner with the National Cancer Institute and opened a facility in Frederick, Maryland. In April 2019, Charles River announced it will be ceasing its San Diego operations, moving the work to one of its sites in Northern California. In California, the company also has sites in the town of Hollister and in South San Francisco. The work done in San Diego—the breeding of rodents that scientists use to test compounds—was moved to Hollister, California. The chairman and chief executive officer isAcquisitions
In October 2003, Charles River Laboratories merged with Inveresk, a research company based in the United Kingdom. The company was known then as Charles River Laboratories. Inveresk specialised in clinical research and pre-clinical testing, and their main facilities are in Edinburgh, Scotland. In late 2009, Charles River sold its Clinical Services Division in Edinburgh to Quotient Bioresearch. In 2010, Charles River Laboratories attempted to acquire WuXi PharmaTech, a China-based contract research organization, but the offer was withdrawn when the deal faced opposition from several large Charles River investors, including Relational Investors, JANA Partners, and Neuberger Berman. Proxy advisory firm RiskMetrics had also recommended that Charles River's shareholders vote against the proposed deal. From 2008 to 2013, Charles River acquires several companies including NewLab Bioquality AG, MIR Preclinical Services, Piedmont Research Center, LLC, Cerebricon, Ltd., Accugenix, and Vital River, allowing the company to expand their research models and services portfolio to drug development and discovery markets in China. The acquisitions of Argenta and BioFocus in 2014 allowed Charles River to establish themselves as a full-service, early-stage contract research organization with integrated ''in vitro'' and ''in vivo'' capabilities from target discovery through pre-clinical development. In July 2015, the company announced it would acquire Celsis International for $212 million. In January 2016, the company announced it was set to acquire WIL Research for approximately $585 million in cash. In June, the company announced it would acquire Blue Stream Laboratories. In August 2017, the business announced it would acquire Brains On-Line. In January 2018, the company announced it would acquire KWS BioTest for up to £18 million ($24.4 million). In February of the same year, Charles River announced it would acquireSee also
*Notes
External links
* {{Authority control Companies listed on the New York Stock Exchange Health care companies established in 1947 Companies based in Wilmington, Massachusetts Multinational companies headquartered in the United States Animal rights Health care companies based in Massachusetts Contract research organizations Animal testing in the United States Animal testing in the United Kingdom 1947 establishments in Massachusetts Life sciences industry 2000 initial public offerings