Charles Alberton Janeway
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Charles Alderson Janeway (1909 in New York City – 1981 in Weston, Massachusetts) was an American
pediatrician Pediatrics ( also spelled ''paediatrics'' or ''pædiatrics'') is the branch of medicine that involves the medical care of infants, children, adolescents, and young adults. In the United Kingdom, paediatrics covers many of their youth until the ...
, medical
professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...
, and clinical researcher. Janeway was physician in chief from 1946 to 1976 at Children's Hospital Boston. He also was Thomas Morgan Rotch Professor of Pediatrics at
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
. As a clinical researcher, he discovered the first
immunodeficiency Immunodeficiency, also known as immunocompromisation, is a state in which the immune system's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that a ...
disease.Haggerty, RJ, and Lovejoy Jr., FH.(2007) ''Charles A. Janeway: Pediatrician to the World's Children'' Cambridge, Massachusetts: Harvard University Press. () According to a 2007 biography by physicians Robert J. Haggerty and Frederick H. Lovejoy Jr.:
"Janeway built the first department of pediatrics in the nation with subspecialties based upon the new developments in basic sciences. Janeway and his colleagues defined the
gamma globulin Gamma globulins are a class of globulins, identified by their position after serum protein electrophoresis. The most significant gamma globulins are immunoglobulins ( antibodies), although some immunoglobulins are not gamma globulins, and some ga ...
disorders that resulted in children's increased susceptibility to infections and associated arthritic disorders. Janeway was the most visible U.S. pediatrician on the world scene in the last half of the 20th century. He traveled widely, taught modern pediatrics to thousands of physicians throughout the developing world, and brought many of them to the U.S. for further training. He was instrumental in starting teaching hospitals in
Shiraz, Iran Shiraz (; fa, شیراز, Širâz ) is the fifth-most-populous city of Iran and the capital of Fars Province, which has been historically known as Pars () and Persis. As of the 2016 national census, the population of the city was 1,565,572 p ...
, and
Cameroon Cameroon (; french: Cameroun, ff, Kamerun), officially the Republic of Cameroon (french: République du Cameroun, links=no), is a country in west-central Africa. It is bordered by Nigeria to the west and north; Chad to the northeast; the C ...
."
In 1964, Janeway worked with the provincial government in St. John's,
Newfoundland Newfoundland and Labrador (; french: Terre-Neuve-et-Labrador; frequently abbreviated as NL) is the easternmost province of Canada, in the country's Atlantic region. The province comprises the island of Newfoundland and the continental region ...
, Canada to establish a children's hospital. In recognition of his efforts and dedication, the hospital was named the Dr. Charles Alderson Janeway Child Health Centre. Its first location was in the former base hospital on Pepperrell Air Force Base which had closed several years earlier. Janeway came from a family of prominent physicians. His father, Theodore Caldwell Janeway, was the first full-time professor of medicine at the Johns Hopkins University School of Medicine and discovered one of the first methods for measuring blood pressure. His grandfather,
Edward Gamaliel Janeway Edward Gamaliel Janeway (August 31, 1841 – February 10, 1911) was an American physician who served as Health Commissioner of New York, and as president of the New York Medical Journal Association in the late nineteenth century. He was considered ...
, served as the Health Commissioner of New York and dean of the combined New York University/Bellevue Hospital medical colleges. Edward G. Janeway also identified of
Janeway lesions Janeway lesions are rare, non-Tenderness (medicine), tender, small erythematous or haemorrhagic macule, macular, papule, papular or Nodule (medicine), nodular lesions on the palms or Sole (foot), soles only a few millimeters in diameter that are as ...
, which are named in his honor. Janeway graduated from Milton Academy in Milton, Massachusetts. He graduated from
Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...
in 1930, where he was a member of Skull and Bones. He also graduated from the Johns Hopkins University School of Medicine. He married Elizabeth Bradley, a social worker, in 1932. They had four children: Anne, Elizabeth, Charles, and Barbara. His medical legacy continued to subsequent generations. His son,
Charles Janeway Charles Alderson Janeway, Jr. (1943–2003) was a noted immunologist who helped create the modern field of innate immunity. A member of the National Academy of Sciences, he held a faculty position at Yale University's Medical School and was ...
(1943–2003), was an immunologist, noted
Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...
medical professor, and member of the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
, who made significant contributions to the field of
innate immune response The innate, or nonspecific, immune system is one of the two main immunity strategies (the other being the adaptive immune system) in vertebrates. The innate immune system is an older evolutionary defense strategy, relatively speaking, and is the ...
. His daughter Barbara is a nurse-practitioner in New Hampshire. Four of his granddaughters are physicians; Elizabeth Gold of Toronto and Katherine A. Janeway of Boston, are also pediatricians, Megan Janeway of Boston is a general surgeon and Hannah Janeway of Los Angeles is an emergency medicine physician representing the sixth generation of Janeway doctors. Charles A. Janeway died at his home in Weston, Massachusetts, in 1981.


References

{{DEFAULTSORT:Janeway, Charles Alderson Janeway, Dr. Charles A. Janeway, Dr. Charles A. Yale University alumni Johns Hopkins University alumni Milton Academy alumni Harvard Medical School faculty Schools in Middlesex County, Massachusetts People from Weston, Massachusetts Physicians from New York City