Chanoclavine-I dehydrogenase (, ''easD (gene)'', ''fgaDH (gene)'') is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''chanoclavine-I:NAD
+ oxidoreductase''.
This enzyme
catalises the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
:
chanoclavine
Chanoclavine, also known as chanoclavin-l is a tri-cyclic ergot alkaloid (ergoline) isolate of certain fungi. It is mainly produced by members of the genus claviceps
Ergot ( ) or ergot fungi refers to a group of fungi of the genus ''Claviceps' ...
-I + NAD
+ chanoclavine-I aldehyde + NADH + H
+
This enzyme catalyses a step in the pathway of
ergot alkaloid
Ergoline is a chemical compound whose structural skeleton is contained in a variety of alkaloids, referred to as ergoline derivatives or ergoline alkaloids. Ergoline alkaloids, one being ergine, were initially characterized in ergot. Some of thes ...
biosynthesis in certain fungi.
References
External links
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