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Cefonicide (or cefonicid) is a cephalosporin antibiotic.
It has a density of 1.92g/cm3.
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Cefonicid is synthesized conveniently by nucleophilic displacement of the 3-acetoxy moiety of 1 with the appropriately substituted tetrazole thiole 2. The mandelic acid amide C-7 side chain is reminiscent of
Synthesis
Injectable semi-synthetic cephalosporin antibiotic related tocefamandole
Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally. Cef ...
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Cefonicid is synthesized conveniently by nucleophilic displacement of the 3-acetoxy moiety of 1 with the appropriately substituted tetrazole thiole 2. The mandelic acid amide C-7 side chain is reminiscent of cefamandole
Cefamandole (INN, also known as cephamandole) is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally. Cef ...
.
See also
*Cefazaflur
Cefazaflur (INN
Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they al ...
References
Acetaldehyde dehydrogenase inhibitors Cephalosporin antibiotics Enantiopure drugs Phenylethanolamines Sulfonic acids Tetrazoles {{antibiotic-stub