Cefalotin ( INN) or cephalothin ( USAN) is a first-generation

cephalosporin The cephalosporins (sg. ) are a class of β-lactam antibiotics originally derived from the fungus ''Acremonium'', which was previously known as ''Cephalosporium''. Together with cephamycins, they constitute a subgroup of β-lactam antibiotics ...

antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...

. It was the first cephalosporin marketed (1964) and continues to be widely used. It is an

intravenous Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrie ...

ly administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is marketed as Keflin ( Lilly) and under other trade names.: Cefalotin The compound is a derivative of

thiophene-2-acetic acid Thiophene-2-acetic acid is the organosulfur compound with the formula HO2CCH2C4H3S. Together with thiophene-3-acetic acid, it is one of two isomeric thiophene acetic acids. Preparation and use It is prepared from 2-acetylthiophene. It is a p ...

References

Cephalosporin antibiotics Eli Lilly and Company brands Thiophenes Acetate esters {{Antibiotic-stub