Cedecea davisae is a

gram-negative Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall ...

motile Motility is the ability of an organism to move independently, using metabolic energy. Definitions Motility, the ability of an organism to move independently, using metabolic energy, can be contrasted with sessility, the state of organisms th ...

, rod-shaped, non-

sporulating In biology, a spore is a unit of sexual reproduction, sexual or asexual reproduction that may be adapted for biological dispersal, dispersal and for survival, often for extended periods of time, in unfavourable conditions. Spores form part of ...

lipase Lipase ( ) is a family of enzymes that catalyzes the hydrolysis of fats. Some lipases display broad substrate scope including esters of cholesterol, phospholipids, and of lipid-soluble vitamins and sphingomyelinases; however, these are usually tr ...

positive bacteria.

Phylogeny and genome evolution

The bacteria falls into the genus ''Cedecae'', which was discovered by the Centers for Disease Control and Prevention in 1977 and determined to be its own genus in 1981. There are five different species within the genus ''Cadecea'': ''C. davisae'', ''C. lapangei'', ''C. netri'', ''Cedecea spp. 3'', and ''Cedecea spp. 5''. The classification of this organism from Kingdom to species is Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, ''Cedecea, davisae''. It is described as an emerging pathogen, due to it being discovered fairly recently.

Metabolic details

''Cedecea davisae'' is a part of the Enterobacteriaceae family. This family is well known for being Chemoorganoheterotrophs and therefore it is safe to assume that ''Cedecea davisae'' is most likely a Chemoorganoheterotroph, meaning it gets its energy and carbon from other sources than itself, although research has not clearly stated this.

Relevance to human health

''Cedecea davisae'' is an opportunistic pathogen, meaning its presence will only cause an infection to its host in the right circumstances. Such conditions can include advanced age, renal disease, Cystic Fibrosis as well as other comorbidities. When ''Cedecea davisae'' is provided with any of these optimal conditions, it can play an important role in a variety of bacterial infections that can take place in the human body. One of the infections that ''Cedecea davisae'' has been found in is a rare bacteremia, the presence of bacteria in circulating blood, in patients with chronic renal disease which causes chills, fever, nausea and diarrhea in its host. It has also been shown that ''Cedecea davisae'' can be found in polymicrobial pulmonary infections in patients who have been diagnosed with Cystic Fibrosis. Other research suggests that it can cause other infections in the skin, soft tissue and lung infections as well as other catheter-related blood infections. With the antibiotic resistance ''Cedecea davisae'' has acquired, it can be difficult to treat such rare infections. The cell walls of the bacterium have few porins giving it a great broad sense antibiotic resistance because drugs have a hard time getting into the periplasm of the bacteria. Additionally, AmpC production splits the beta lactam ring that is essential for the drug to harm bioactivity within the bacteria.

Phylogeny and genome evolution

Metabolic details

Relevance to human health

References

Further reading