Caspase-10 (, ''FLICE2, Mch4'', ''CASP-10'', ''ICE-like apoptotic protease 4'', ''apoptotic protease Mch-4'', ''FAS-associated death domain protein interleukin-1beta-converting enzyme 2'') is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...

. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...

: Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Leu-Gln-Thr-Asp!Gly Caspase-10 is an initiator

caspase Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing essential roles in programmed cell death. They are named caspases due to their specific cystei ...

, as are caspase-2 ( EC 3.4.22.55), caspase-8 ( EC 3.4.22.61) and caspase-9 ( EC 3.4.22.62).

References

External links

* {{Portal bar, Biology, border=no EC 3.4.22