Cara Tannenbaum
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Cara Tannenbaum is a Canadian researcher and practicing physician in the fields of geriatrics, women's health and gender research. Since 2015, Tannenbaum has served as the Scientific Director of Canadian Institutes of Health Research's Institute of Gender and Health. She was appointed as a Member of the
Order of Canada The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the ...
on November 17, 2021.


Career

Tannenbaum completed medical school (1994), additional training in geriatrics (2000), and a
Master of Science A Master of Science ( la, Magisterii Scientiae; abbreviated MS, M.S., MSc, M.Sc., SM, S.M., ScM or Sc.M.) is a master's degree in the field of science awarded by universities in many countries or a person holding such a degree. In contrast to ...
degree in
epidemiology Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
and
biostatistics Biostatistics (also known as biometry) are the development and application of statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experime ...
(2002) at
McGill University McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec, Canada. Founded in 1821 by royal charter granted by King George IV,Frost, Stanley Brice. ''McGill Universit ...
. She is now a professor of medicine and pharmacy at the
Université de Montréal The Université de Montréal (UdeM; ; translates to University of Montreal) is a French-language public research university in Montreal, Quebec, Canada. The university's main campus is located in the Côte-des-Neiges neighborhood of Côte-de ...
, where she conducts research at the Centre de recherche de l’Institut universitaire de gériatrie de Montréal. In 2015, Tannenbaum was appointed as the Scientific Director of the Institute of Gender and Health at the Canadian Institutes of Health Research, and was appointed as the Departmental Science Advisor for
Health Canada Health Canada (HC; french: Santé Canada, SC)Health Canada is the applied title under the Federal Identity Program; the legal title is Department of Health (). is the Structure of the Canadian federal government#Departments, with subsidiary unit ...
in 2019.


Research

Tannenbaum was initially involved in the EMPOWER (Eliminating Medications Through Patient Ownership of End Results) trial, which is an educational intervention (using a theory-based patient handout) to engage older adults with their pharmacist or physician in discontinuing inappropriate medication. The EMPOWER trial resulted in 27% of participants in the intervention group discontinuing their
benzodiazepine Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, ...
use (compared with 5% of the
control group In the design of experiments, hypotheses are applied to experimental units in a treatment group. In comparative experiments, members of a control group receive a standard treatment, a placebo, or no treatment at all. There may be more than one tr ...
) at six months. Through this trial, Tannenbaum and her colleagues found that two-thirds of individuals who received EMPOWER handouts had taken it to their doctor or pharmacist, but in about half of these instances, the health care professionals discouraged
deprescribing Deprescribing is the planned and supervised process of intentionally stopping a medication or reducing its dose to improve the person's health or reduce the risk of adverse side effects. Deprescribing is usually done because the drug may be causin ...
. This prompted Tannenbaum to launch and oversee the D-PRESCRIBE clinical trial, which tested whether a pharmacist-led educational intervention could decrease the number of prescriptions issued for inappropriate medication among 489 older adults in
Quebec Quebec ( ; )According to the Canadian government, ''Québec'' (with the acute accent) is the official name in Canadian French and ''Quebec'' (without the accent) is the province's official name in Canadian English is one of the thirtee ...
. The trial found that a pharmacist intervention resulted in greater medication discontinuation (43%) at six months than those receiving regular care. Between May 2013 and July 2017, Tannenbaum led the international "Dare to Age Well for Women" urinary incontinence trial (also referred to as the CACTUS-D i.e. Continence Across Continents To Upend Stigma and Dependency), which was a
randomised controlled trial A randomized controlled trial (or randomized control trial; RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical t ...
to test the effect of a continence promotion intervention on the urinary symptoms and quality of life in 910 women, aged 65 or older, in the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
,
France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pac ...
and
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tot ...
(
Alberta Alberta ( ) is one of the thirteen provinces and territories of Canada. It is part of Western Canada and is one of the three prairie provinces. Alberta is bordered by British Columbia to the west, Saskatchewan to the east, the Northwest Ter ...
, Quebec). So far, results from the women recruited from the UK indicate that participants in the combined intervention group had the highest rate of urinary symptom improvement, and that the recruitment rate for local community organizations was as high as 44%. Tannenbaum co-founded the Canadian Deprescribing Network (CaDeN), and previously served as a co-director. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, Tannenbaum has served on the Canada Chief Science Advisor's Expert Group on Health Systems, and helped lead the implementation efforts for CanCOVID, a Canada-wide network of over 3,000 health, science and policy researchers to facilitate COVID-19 research collaboration. With
Holly Witteman Holly Witteman is a health informatics researcher. She is a Full Professor (''professeure titulaire'') in the Department of Family & Emergency Medicine at the Université Laval, in Quebec City, Canada. Witteman is the Canada Research Chair (Tier ...
and Jenna Haverfield, Tannenbaum found that when the Canadian Institutes of Health Research implemented data-driven gender policy interventions in a second COVID-19 funding competition (April-May 2020), the funding competition received more grant applications from female scientists, and received and funded more grant applications which considered sex and gender in their study design. Tannenbaum has published over 200 academic publications, which have been cited over 6,500 times, resulting in a
h-index The ''h''-index is an author-level metric that measures both the productivity and citation impact of the publications, initially used for an individual scientist or scholar. The ''h''-index correlates with obvious success indicators such as winn ...
and i10-index of 42 and 101 respectively.


Awards, honours and public engagement

In 2018, Tannenbaum was inducted as a fellow of the
Canadian Academy of Health Sciences The Canadian Academy of Health Sciences (CAHS) is one of three national academies that comprise the Council of Canadian Academies (CCA), the highest honour granted to scholars in Canada. The two other CCA academies are the Royal Society of Canada ...
. She has been awarded the Association of Faculties of Medicine of Canada's May-Cohen Gender Equity Award, the Canadian Institutes of Health Research's Betty Haven's Knowledge Transfer Prize in Aging, the
Society of Chemical Industry The Society of Chemical Industry (SCI) is a learned society set up in 1881 "to further the application of chemistry and related sciences for the public benefit". Offices The society's headquarters is in Belgrave Square, London. There are semi-in ...
Purvis Memorial Award (2020) and the American Society for Clinical Pharmacology & Therapeutics' William B. Abrams Awards in Geriatric Clinical Pharmacology (2021), and is the Michel-Saucier Endowed Chair in Geriatric Pharmacology, Health and Aging. In 2020, Tannenbaum was awarded the Canadian Science Policy Centre's Exceptional Contribution to Science Policy Award: Trailblazer Award. On November 17, 2021, Tannenbaum was appointed as a Member of the
Order of Canada The Order of Canada (french: Ordre du Canada; abbreviated as OC) is a Canadian state order and the second-highest honour for merit in the system of orders, decorations, and medals of Canada, after the Order of Merit. To coincide with the ...
for "her leadership in geriatrics, women’s health and gender research, and for her inter-professional collaborations to optimize healthy aging across the lifespan". Tannenbaum has also written editorials regarding various issues related to her research expertise, including an editorial in
The BMJ ''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Origi ...
to address the International Association of Athletics Federations' new "differences of sex development" rules causing
Caster Semenya Mokgadi Caster Semenya OIB (born 7 January 1991) is a South African middle-distance runner and winner of two Olympic gold medals and three World Championships in the women's 800 metres. She first won gold at the World Championships in 2009 ...
to no longer be eligible, and why sex and gender matter in
implementation research Implementation research is the systematic study of methods that support the application of research findings and other evidence-based knowledge into policy and practice. It aims to understand the most effective pathways from research to practical a ...
in the
BMC Medical Research Methodology BioMed Central (BMC) is a United Kingdom-based, for-profit scientific open access publisher that produces over 250 scientific journals. All its journals are published online only. BioMed Central describes itself as the first and largest open a ...
.


Selected Bibliography

* Tannenbaum, Cara, Philippe Martin, Robyn Tamblyn, Andrea Benedetti, and Sara Ahmed. "Reduction of inappropriate benzodiazepine prescriptions among older adults through direct patient education: the EMPOWER cluster randomized trial." ''
JAMA Internal Medicine ''JAMA Internal Medicine'' is a monthly peer-reviewed medical journal published by the American Medical Association. It was established in 1908 as the ''Archives of Internal Medicine'' and obtained its current title in 2013. It covers all aspects ...
'' 174, no. 6 (2014): 890-898. * Tannenbaum, Cara, Julie Clark, Kevin Schwartzman, Sylvan Wallenstein, Robert Lapinski, Diane Meier, and Marjorie Luckey. "Yield of laboratory testing to identify secondary contributors to osteoporosis in otherwise healthy women." '' The Journal of Clinical Endocrinology & Metabolism'' 87, no. 10 (2002): 4431-4437. * Andersson, Karl-Erik, Christopher R. Chapple, Linda Cardozo, Francisco Cruz, Hashim Hashim, Martin C. Michel, Cara Tannenbaum, and Alan J. Wein. "Pharmacological treatment of overactive bladder: report from the International Consultation on Incontinence." '' Current Opinion in Urology'' 19, no. 4 (2009): 380-394. * Tannenbaum, Cara, Amélie Paquette, Sarah Hilmer, Jayna Holroyd-Leduc, and Ryan Carnahan. "A systematic review of amnestic and non-amnestic mild cognitive impairment induced by anticholinergic, antihistamine, GABAergic and opioid drugs." '' Drugs & Aging'' 29, no. 8 (2012): 639-658.


References

{{DEFAULTSORT:Tannenbaum, Cara Year of birth missing (living people) Living people Université de Montréal faculty McGill University alumni Fellows of the Canadian Academy of Health Sciences Canadian women physicians Canadian geriatricians Women geriatricians 21st-century Canadian physicians Members of the Order of Canada