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Black salve, also known by the brand name Cansema, is a pseudoscientific
alternative cancer treatment Alternative cancer treatment describes any cancer treatment or practice that is not part of the conventional standard of cancer care. These include special diets and exercises, chemicals, herbs, devices, and manual procedures. Most alternative ...
. The product is commonly classified as an escharotic—a topical paste which destroys skin tissue and leaves behind a scar called an
eschar An eschar (; Greek: ''ἐσχάρᾱ'', ''eskhara''; Latin: ''eschara'') is a slough or piece of dead tissue that is cast off from the surface of the skin, particularly after a burn injury, but also seen in gangrene, ulcer, fungal infections, ...
. Escharotics were widely used to treat skin lesions in the early 1900s, but have since been replaced by safer and more effective treatments. Escharotics, such as black salves, are currently advertised by some alternative medicine marketers as treatments for
skin cancer Skin cancers are cancers that arise from the skin. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of skin cancers: basal-cell skin cancer (BCC) ...
, often with unsubstantiated testimonials and unsupported claims of effectiveness. The
U.S. Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
has listed Cansema as a "fake cancer cure" and warns consumers to avoid it.


Usages and dangers

Cancer salves were first utilized during the Victorian period. As the medical profession started to gain better understanding, many home remedies, black salve as one example started to be criticized by medical professionals. An example of this is documented and labeled as a form of
quackery Quackery, often synonymous with health fraud, is the promotion of fraudulent or ignorant medical practices. A quack is a "fraudulent or ignorant pretender to medical skill" or "a person who pretends, professionally or publicly, to have skill, ...
in a 1955 ''
Time Time is the continued sequence of existence and events that occurs in an apparently irreversible succession from the past, through the present, into the future. It is a component quantity of various measurements used to sequence events, ...
'' magazine article: They are not recommended as treatments for skin lesions or skin cancer by medical authorities, but are marketed as such by some alternative medicine practitioners. Use of escharotics, particularly when used instead of proven treatments, can be dangerous. The escharotic may not remove all of the cancerous cells, and frequently removes healthy tissue. Practitioners who use or sell escharotics frequently provide testimonials, in place of scientific evidence, to convince others of effectiveness and safety which does not exist. Safer and more effective treatments exist for skin cancers, such as:
cryotherapy Cryotherapy, sometimes known as cold therapy, is the local or general use of low temperatures in medical therapy. Cryotherapy may be used to treat a variety of tissue lesions. The most prominent use of the term refers to the surgical treatment, s ...
; topical agents such as
imiquimod Imiquimod, sold under the brand name Aldara among others, is a medication that acts as an immune response modifier that is used to treat genital warts, superficial basal cell carcinoma, and actinic keratosis. Scientists at 3M's pharmaceuticals ...
,
fluorouracil Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. By intravenous injection it is used for treatment of colorectal cancer, oesophageal cancer, stomach cancer, pan ...
and ingenol mebutate;
radiation therapy Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radi ...
; and surgical excision, including
Mohs surgery Mohs surgery, developed in 1938 by a general surgeon, Frederic E. Mohs, is microscopically controlled surgery used to treat both common and rare types of skin cancer. During the surgery, after each removal of tissue and while the patient waits, ...
(microscopically controlled surgery used to remove and test cancerous tissue). Escharotics can cause serious scarring and damage to normal skin. Their manufacture is largely unregulated, so the strength and purity of marketed products are unknown and unverified. Numerous reports in the medical literature describe serious consequences of using escharotics in place of standard treatments for skin cancer, ranging from disfigurement to preventable cancer recurrences. The website
Quackwatch Quackwatch is a United States-based website, self-described as a "network of people" founded by Stephen Barrett, which aims to "combat health-related frauds, myths, fads, fallacies, and misconduct" and to focus on "quackery-related information th ...
warned against the use of escharotics in 2008, with a collection of sourced documents compiling issues of patient injury from their use. A more recent study revealed that many individuals who have used black salve were unaware of its potential dangers. In 2016, the American Academy of Dermatology urged patients to consult a
dermatologist Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medica ...
before using home remedies for skin cancers. Furthermore, individuals increase their risk of further complications or death if they choose to delay conventional medical treatment to attempt treatment with black salve. In 2017, a patient with breast cancer posted photos and updates to a black salve research group as she progressed through her black salve applications. Despite her worsening condition, she truly believed that the black salve was going to cure her cancer. "And please no comments to see a doctor. I've been there. This is my path and I trust in it and my God who is healing me", she wrote. Eventually she sought conventional treatment, but died of a prolonged infection some months later. It was reported in 2018 that the use of black salve had been expanded to include pets. In a Facebook group, people described the use of black salve on cats, dogs and horses. In 2018, black salve was strongly linked to the death of Helen Lawson in Australia. Lawson covered her abdomen in black salve under the direction of
Dennis Wayne Jensen Dennis or Denis is a first or last name from the Greco-Roman name Dionysius, via one of the Christian saints named Dionysius. The name came from Dionysus, the Greek god of ecstatic states, particularly those produced by wine, which is someti ...
, a self-proclaimed healer, who advised her that it would draw out her ovarian cancer. The black salve left Lawson with a mass of wounds on her abdomen, which became so large that surgeons could not operate on it within a few weeks. Lawson's sister-in-law described the wounds as extending from "above her pubic bone, all across her abdomen almost up to her rib cage", and as "raw, mutilated bubbling flesh". Lawson died in April 2018. In 2019, Jensen was issued a prohibition order by the
Health Complaints Commissioner Health, according to the World Health Organization, is "a state of complete physical, Mental health, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World H ...
of Victoria, forbidding him permanently from providing substances which "he (or anyone else) claims can cure or treat cancer or other serious disease or illness". This includes black salve.


Ingredients

Common ingredients of black salves include
zinc chloride Zinc chloride is the name of inorganic chemical compounds with the formula ZnCl2 and its hydrates. Zinc chlorides, of which nine crystalline forms are known, are colorless or white, and are highly soluble in water. This salt is hygroscopic and e ...
, chaparral (also known as creosote bush), and often
bloodroot ''Sanguinaria canadensis'', bloodroot, is a perennial, herbaceous flowering plant native to eastern North America. It is the only species in the genus ''Sanguinaria'', included in the poppy family Papaveraceae, and is most closely related to ' ...
, a plant frequently used in herbal medicine. The extract of bloodroot is called
sanguinarine Sanguinarine is a polycyclic quaternary alkaloid. It is extracted from some plants, including the bloodroot plant, from whose taxonomic name, ''Sanguinaria canadensis,'' its name is drawn; the Mexican prickly poppy (''Argemone mexicana''); ''Chel ...
, a quaternary benzophenanthridine
alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...
which attacks and destroys living tissue and is also classified as an escharotic. Other formulations include the four ingredients:
red clover ''Trifolium pratense'', the red clover, is a herbaceous species of flowering plant in the bean family Fabaceae, native to Europe, Western Asia, and northwest Africa, but planted and naturalized in many other regions. Description Red clove ...
,
galangal Galangal () is a common name for several tropical rhizomatous spices. Differentiation The word ''galangal'', or its variant ''galanga'' or archaically ''galingale'', can refer in common usage to the aromatic rhizome of any of four plant spec ...
, sheep sorrel, and
bloodroot ''Sanguinaria canadensis'', bloodroot, is a perennial, herbaceous flowering plant native to eastern North America. It is the only species in the genus ''Sanguinaria'', included in the poppy family Papaveraceae, and is most closely related to ' ...
, crushed into a paste using mortar and pestle. Pseudoscientific practitioners advise that this is applied sparingly to the affected area, and kept covered for 2–3 days, although this treatment has not been proven to work for any medical application or to be safe.


Regulation


Australia

The
Therapeutic Goods Administration The Therapeutic Goods Administration (TGA) is the medicine and therapeutic regulatory agency of the Australian Government. As part of the Department of Health and Aged Care, the TGA regulates the quality, supply and advertising of medicines, p ...
(TGA) of Australia is advising consumers against purchasing or using black salve, red salve or Cansema products. The TGA has found the Australian Vaccination-Skeptics Network (AVN) in breach of advertising regulations, and in a separate finding the AVN's former president Meryl Dorey together with Leon Pittard of Fair Dinkum Radio were found to be in breach.


United States

Cansema is listed by the
U.S. Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
(FDA) as one of 187 fake cancer cures. Cansema continues to be marketed by numerous individuals, as evidenced by recent
FDA Warning Letter An FDA warning letter is an official message from the United States Food and Drug Administration (FDA) to a manufacturer or other organization that has violated some rule in a federally regulated activity. The FDA defines an FDA warning letter as: ...
s. The FDA has taken enforcement action against illegal marketing of Cansema as a cancer cure, as in the 2004 arrest and conviction of Greg Caton. The FDA has taken an active role in the banning of these chemicals for use as a cancer cure. Typical warning letters detail the dangers of this product while also admonishing the purveyors of their obligation to comply with federal law. Summaries of recent letters are cataloged on the FDA website.


See also

*
List of ineffective cancer treatments This is a non-exhaustive list of alternative treatments that have been promoted to treat or prevent cancer in humans but which lack scientific and medical evidence of effectiveness. In many cases, there is scientific evidence that the alleged tr ...


References


Further reading

* Hurley D. ''Natural Causes: Death, Lies, and Politics in America's Vitamin and Herbal Supplement Industry''. New York: Broadway Books, 2006. {{ISBN, 0-7679-2042-2


External links


Escharotics information
New Zealand Dermatological Society
"Bloodroot"
Sloan-Kettering Cancer Center Herbal Database. Retrieved July 28, 2021.
Escharotics information
Therapeutic Goods Administration
Photo series illustrating harmful effects of black salve treatment.
Alternative medicine Alternative cancer treatments Pseudoscience