The Cannabinoid Research Initiative of Saskatchewan (CRIS) was founded in 2017 as an interdisciplinary research team of clinician researchers (medical and veterinary), basic scientists, and social scientists. CRIS aims to obtain scientific evidence about the application of

Cannabinoids Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...

and

Medical cannabis Medical cannabis, or medical marijuana (MMJ), is cannabis and cannabinoids that are prescribed by physicians for their patients. The use of cannabis as medicine has not been rigorously tested due to production and governmental restrictions ...

to humans and animals, for health, disease and disorders. The team was initially based at the

University of Saskatchewan A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, t ...

, in

Saskatoon Saskatoon () is the largest city in the Provinces and territories of Canada, Canadian province of Saskatchewan. It straddles a bend in the South Saskatchewan River in the central region of the province. It is located along the Trans-Canada Hig ...

Saskatchewan Saskatchewan ( ; ) is a Provinces and territories of Canada, province in Western Canada, western Canada, bordered on the west by Alberta, on the north by the Northwest Territories, on the east by Manitoba, to the northeast by Nunavut, and on t ...

, Canada but includes researchers based at the

University of Regina The University of Regina is a public university, public research university located in Regina, Saskatchewan, Canada. Founded in 1911 as a private denominational high school of the Methodist Church of Canada, it began an association with the Unive ...

and

University of Alberta The University of Alberta, also known as U of A or UAlberta, is a public research university located in Edmonton, Alberta, Canada. It was founded in 1908 by Alexander Cameron Rutherford,"A Gentleman of Strathcona – Alexander Cameron Rutherfor ...

. A strategic management executive committee coordinates activities and develops research opportunities. The sections of CRIS include: Analytical Evaluations, Human Clinical Studies, Biomedical studies, Veterinary Sciences, Knowledge Translation and Studies of Cannabinoids and Society. CRIS members participate in the Canadian Consortium for the Investigation of Cannabinoids, and the International Cannabinoid Research Society. The CARE-E clinical trial of a cannabis oil with high cannabidiol content with pediatric patients with refractory epilepsy was a key factor in initiating the research initiative. The CARE-E trial is a multi-center phase one trial that currently has open enrollment in five Canadian cities. The CARE-E trial received extensive media coverage when it was launched. The therapeutic effect of pure cannabidiol (Epidiolex

GW Pharmaceuticals GW Pharmaceuticals is a British pharmaceutics company known for its multiple sclerosis treatment product nabiximols (brand name, Sativex) which was the first natural cannabis plant derivative to gain market approval in any country. Another cannab ...

) on Dravet Syndrome was recently reported in the New England Journal of Medicine The CRIS group has expanded to biomedical science studies of the pharmacology of cannabinoids and synthetic cannabinoids.

Laboratories

* Drug Discovery Research Group - :(i) Determinants of neonatal exposure risk when breastfeeding mothers require medications. :(ii) Research into the health benefits of flaxseed lignans and their underlying mechanism(s) of action. * Multiple Sclerosis Research - (i) Epidemiology and pharmacoepidemiology of MS. * Clinical trials :(i) Clinical trials looking at cannabis in pediatric neurological disease. :(ii) Neuro-degenerative and neuro-metabolic disorders of childhood * Type 1 cannabinoid receptor (CB1R) Pharmacology of the endocannabinoid system and the type 1 cannabinoid receptor (CB1R). * Microbiome studies Project under development by the Links Lab * Knowledge Translation Medication adherence, patient education and interprofessional education. * Chronic Disease studies Use of interdisciplinary teams in chronic disease management, focusing on delivering diabetes care to immigrant and Aboriginal populations.

External links

'Cannabinoid Research Initiative of Saskatchewan'

'Canadian Consortium for the Investigation of Cannabinoids'

'International Cannabinoid Research Society'

References

{{Authority control Cannabis in Saskatchewan 2017 in cannabis University of Saskatchewan

Laboratories

External links

See also

References