Cannabicitran (CBTC) is a
phytocannabinoid
Cannabinoids () are several structural classes of compounds found in the cannabis plant primarily and most animal organisms (although insects lack such receptors) or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tet ...
first isolated in 1974 as a trace component of ''
Cannabis sativa
''Cannabis sativa'' is an annual Herbaceous plant, herbaceous flowering plant indigenous to East Asia, Eastern Asia, but now of cosmopolitan distribution due to widespread cultivation. It has been cultivated throughout recorded history, used as ...
'',
Structurally related compounds can be found in some other plants.
It is not psychoactive, but was found to reduce
intraocular pressure
Intraocular pressure (IOP) is the fluid pressure inside the eye. Tonometry is the method eye care professionals use to determine this. IOP is an important aspect in the evaluation of patients at risk of glaucoma. Most tonometers are calibrated to ...
in tests on rabbits,
which may reflect agonist activity at the
NAGly receptor
''N''-Arachidonyl glycine receptor (NAGly receptor), also known as G protein-coupled receptor 18 (GPR18), is a protein that in humans is encoded by the ''GPR18'' gene. Along with the other previously "orphan" receptors GPR55 and GPR119, GPR18 ha ...
(formally GPR18) that is known to be a target of many structurally related cannabinoids.
See also
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9-OH-HHC
9-Hydroxyhexahydrocannabinol (9-OH-HHC) is a semi-synthetic derivative of tetrahydrocannabinol. It is formed as an impurity in the synthesis of Delta-8-THC, and retains activity in animal studies though with only around 1/10 the potency of Δ9-TH ...
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Cannabichromene
Cannabichromene (CBC), also called cannabichrome, cannanbichromene, pentylcannabichromene or cannabinochromene, is an anti-inflammatory which may contribute to the pain-killing effect of cannabis.
It is one of the hundreds of cannabinoids found i ...
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Cannabicyclol
Cannabicyclol (CBL) is a non- psychoactive cannabinoid found in ''Cannabis''. CBL is a degradative product like cannabinol, with cannabichromene degrading into CBL through natural irradiation or under acid conditions.
CBL is not scheduled under ...
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Cannabidiol dimethyl ether
Cannabidiol dimethyl ether (CBDD) is a trace component of cannabis which can also be made synthetically. It is a potent and selective inhibitor of the enzyme 15-lipoxygenase and inhibits oxygenation of linoleic acid, a process involved in the d ...
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Cannabielsoin
Cannabielsoin (CBE) is a metabolite of cannabidiol, one of the major chemical components of cannabis.
History
Cannabielsoin in scientific journals was first cited in 1973. It was concluded that cannabielsoin was formed from cannabidiol as part ...
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Cannabigerol
Cannabigerol (CBG) is one of more than 120 identified cannabinoid compounds found in the plant genus ''Cannabis''. Cannabigerol is the decarboxylated form of cannabigerolic acid, the parent molecule from which other cannabinoids are synthesized. ...
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Cannabimovone
Cannabimovone (CBM) is a phytocannabinoid first isolated from a non-psychoactive strain of ''Cannabis sativa'' in 2010, which is thought to be a rearrangement product of cannabidiol. It lacks affinity for cannabinoid receptors, but acts as an ago ...
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Cannabitriol
Cannabitriol ((+)-CBT, (''S'',''S'')-9,10-Dihydroxy-Δ6a(10a)-THC) is a phytocannabinoid first isolated in 1966, an oxidation product of tetrahydrocannabinol which has been identified both as a trace component of cannabis and as a metabolite in ...
References
Benzochromenes
Phytocannabinoids
Heterocyclic compounds with 4 rings
Oxygen heterocycles
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