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Calorad Classic is a liquid
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
weight loss Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other conn ...
supplement which was first introduced to the US and Canadian marketplace in 1984. It has been advertised on both
television Television, sometimes shortened to TV, is a telecommunication medium for transmitting moving images and sound. The term can refer to a television set, or the medium of television transmission. Television is a mass medium for advertisin ...
and
radio Radio is the technology of signaling and communicating using radio waves. Radio waves are electromagnetic waves of frequency between 30 hertz (Hz) and 300 gigahertz (GHz). They are generated by an electronic device called a transmit ...
. Calorad Classic is manufactured by NutriDiem and is marketed by several companies including Essentially Yours Industries and Nysante, all of which are headquartered in
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tot ...
.


Composition

Calorad Classic is a liquid dietary supplement composed primarily of 3,000 mg (3 grams) of Type II
hydrolyzed collagen Gelatin or gelatine (from la, gelatus meaning "stiff" or "frozen") is a translucent, colorless, flavorless food ingredient, commonly derived from collagen taken from animal body parts. It is brittle when dry and rubbery when moist. It may also ...
(hydrolysate) from either beef (bovine) or tuna (marine) sources and 8 mg of
aloe vera ''Aloe vera'' () is a succulent plant species of the genus ''Aloe''. It is widely distributed, and is considered an invasive species in many world regions. An evergreen perennial, it originates from the Arabian Peninsula, but grows wild in tro ...
, both of which are listed as active ingredients. The supplement label states that Calorad is
fat In nutrition science, nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such chemical compound, compounds, most commonly those that occur in living beings or in food. The term often refers spec ...
-free and
carbohydrate In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or ma ...
-free and that 1 serving (1/2 ounce) provides 3 grams of protein and 10
calories The calorie is a unit of energy. For historical reasons, two main definitions of "calorie" are in wide use. The large calorie, food calorie, or kilogram calorie was originally defined as the amount of heat needed to raise the temperature of on ...
. Calorad Classic also comes in a
Kosher (also or , ) is a set of dietary laws dealing with the foods that Jewish people are permitted to eat and how those foods must be prepared according to Jewish law. Food that may be consumed is deemed kosher ( in English, yi, כּשר), fro ...
formulation (marine). The primary claim made for the product is that regular use causes weight loss without loss of lean
muscle Skeletal muscles (commonly referred to as muscles) are organs of the vertebrate muscular system and typically are attached by tendons to bones of a skeleton. The muscle cells of skeletal muscles are much longer than in the other types of muscl ...
mass. While weight loss and
body fat Adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes. In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular en ...
reduction may be achieved simply by following the labeled instruction to avoid eating within three hours prior to sleep as that can result in eating fewer calories per day, most individuals fasting for 3-hours prior to bed-time alone are not successful in accomplishing long-term weight loss. Formulator Michel Grise stated that the original version of what later became known as Calorad was developed to treat chickens with fatty liver syndrome. Chickens were developing so much body fat that they stopped laying eggs. The formulation was successful in helping farmers reduce body fat of chickens to get them laying eggs again. This led to the question of whether such a product would work for humans.


Scientific studies

Although the manufacturer does not make claims for Calorad Classic in the treatment or cure of disease, the manufacturer does cite published clinical trials in OsteoArthritis and Osteoporosis, Rheumatoid Arthritis, and Fibromyalgia all conducted with Type II hydrolyzed collagen (collagen hydrolysate), the primary ingredient in Calorad. The manufacturer claims that 40% of subjects will lose weight within 1 month, 75% after 2 months and 87% after 3 months. The distributors of the product offer a 30-day satisfaction guarantee. In support of these claims, the distributing companies cite a clinical study of Calorad (also unpublished and non-peer reviewed) by Joel B. Lao. Lao is a Doctor of Internal Medicine, and medical consultant in the
Philippines The Philippines (; fil, Pilipinas, links=no), officially the Republic of the Philippines ( fil, Republika ng Pilipinas, links=no), * bik, Republika kan Filipinas * ceb, Republika sa Pilipinas * cbk, República de Filipinas * hil, Republ ...
who studied the effects of Calorad and its effect on overweight and/or obese individuals. The subjects included 50 overweight or obese individuals who were observed over a 90-day period. One bottle of Calorad was provided to each of the subjects every month for a 3-month period. In month 1, the average weight loss was 5.7 pounds. By month 3, subjects had an average reduction of 10 pounds, and an average inch loss at the waist of 3 inches. The claim that Calorad Classic facilitates weight loss while building or maintaining lean muscle mass is based upon an unpublished and non-peer reviewed study by Davis ''et al.'' in which 300 subjects between the ages of 17–77 years, were followed for 1 year, and the majority of whom lost weight (an average of 3.75 pounds per month) but maintained lean muscle mass. Davis states: "We also found that in the entire group, less than 0.6, or less than 1 per cent, had any loss of lean muscle mass. And 36 per cent of the group actually gained lean muscle mass during that time."


Marketing claims

One of the marketing companies, Essentially Yours, states that most subjects on a weight loss regimen lose lean muscle mass along with fat and water weight, so that maintaining lean muscle mass is a benefit seen with Calorad Classic users. When first introduced, the manufacturer claimed that Calorad Classic could cause the user to "lose weight while you sleep", repair joints, and prevent or reduce the symptoms of arthritis. The manufacturer has since dropped these claims because they are "medical treatment claims" and require a drug treatment classification approved by the United States
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
, and are usually only granted following submission of large clinical trials similar to those conducted by pharmaceutical companies in substantiation of these claims. Neither the manufacturer (Nutridiem) or the distributing companies (Nysante or EYI) have conducted this type of rigorous trial on Calorad in support of such claims. The manufacturer and distributing companies have replaced these claims with the current claim that Calorad "promotes sleep and improves the health and appearance of hair, nails and skin" (all of which are not medical treatment claims). Calorad Classic, like all nutritional supplements, has not been evaluated by the
US Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food s ...
, and all marketing materials related to the product carry a disclaimer to the effect that it is "a
food supplement A dietary supplement is a manufactured product intended to supplement one's diet by taking a pill, capsule, tablet, powder, or liquid. A supplement can provide nutrients either extracted from food sources or that are synthetic in order ...
and is not intended to diagnose, treat, cure, or prevent any disease."


References

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External links


A critical assessment of Calorad

PhenQ reviews
Dietary supplements