Cytochrome P450, family 9, also known as CYP9, is a

cytochrome P450 Cytochromes P450 (CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are ...

family Family (from la, familia) is a Social group, group of people related either by consanguinity (by recognized birth) or Affinity (law), affinity (by marriage or other relationship). The purpose of the family is to maintain the well-being of its ...

found in

Insect Insects (from Latin ') are pancrustacean hexapod invertebrates of the class Insecta. They are the largest group within the arthropod phylum. Insects have a chitinous exoskeleton, a three-part body ( head, thorax and abdomen), three pairs ...

genome In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding ge ...

, CYP9 and insect

CYP6 family Cytochrome P450, family 6, also known as CYP6, is a cytochrome P450 family found in Insect genome. CYP6 and CYP9, another insect CYP family, belong to the same clan as mammalian CYP3 and CYP5 families. The first two CYP6 subfamilies represented ...

belong to the same clan as mammalian

CYP3 Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compo ...

and CYP5 families. The first gene identified in this family is the CYP9A1 from the ''

Heliothis virescens ''Chloridea virescens'', commonly known as the tobacco budworm, is a moth of the family Noctuidae found throughout the eastern and southwestern United States along with parts of Central America and South America. It is a major pest of field cro ...

'' (

tobacco budworm ''Helicoverpa armigera'' is a species of Lepidoptera in the family Noctuidae. It is known as the cotton bollworm, corn earworm, Old World (African) bollworm, or scarce bordered straw (the lattermost in the UK, where it is a migrant). The larvae f ...

), which is involved in thiodicarb

insecticide resistance Pesticide resistance describes the decreased susceptibility of a pest population to a pesticide that was previously effective at controlling the pest. Pest species evolve pesticide resistance via natural selection: the most resistant specimens su ...

. Subfamily CYP9A in

Lepidopteran Lepidoptera ( ) is an order of insects that includes butterflies and moths (both are called lepidopterans). About 180,000 species of the Lepidoptera are described, in 126 families and 46 superfamilies, 10 percent of the total described specie ...

play important roles in insecticide resistance, can metabolize

esfenvalerate Esfenvalerate is a synthetic pyrethroid insecticide marketed under the brand Asana. It is the (''S'')-enantiomer of fenvalerate Fenvalerate is a synthetic pyrethroid insecticide. It is a mixture of four optical isomers which have different in ...

efficiently.

References

Insect genes 9 Protein families {{genetics-stub