The Cardiff University Brain Research Imaging Centre (CUBRIC) is a brain imaging centre, part of

Cardiff University , latin_name = , image_name = Shield of the University of Cardiff.svg , image_size = 150px , caption = Coat of arms of Cardiff University , motto = cy, Gwirionedd, Undod a Chytgord , mottoeng = Truth, Unity and Concord , established = 1 ...

's Science and Innovation Campus in

Cardiff Cardiff (; cy, Caerdydd ) is the capital and largest city of Wales. It forms a principal area, officially known as the City and County of Cardiff ( cy, Dinas a Sir Caerdydd, links=no), and the city is the eleventh-largest in the United Kingd ...

Wales Wales ( cy, Cymru ) is a Countries of the United Kingdom, country that is part of the United Kingdom. It is bordered by England to the Wales–England border, east, the Irish Sea to the north and west, the Celtic Sea to the south west and the ...

, United Kingdom. When it expanded in 2016, it was considered the most advanced brain imaging centre in Europe.

Building

Construction

CUBRIC was established in the Cathays Park campus of Cardiff University in 2006, and moved to a new building in the Maindy Park campus in June 2016. The new building was constructed on old railway land, with the railway aiding in the delivery of the larger scanners. It cost £44,000,000, partially funded by Cardiff University, and partially by the

Welsh Government The Welsh Government ( cy, Llywodraeth Cymru) is the Welsh devolution, devolved government of Wales. The government consists of ministers and Minister (government), deputy ministers, and also of a Counsel General for Wales, counsel general. Minist ...

. It was officially opened by

Queen Elizabeth II Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until Death and state funeral of Elizabeth II, her death in 2022. She was queen ...

on 7 June 2016.

Awards

The new building was awarded the title of Life Science Research Building 2017 by the UK Science Park Association. It also received the "Project of the Year" and "Design Through Innovation" awards from the Royal Institution of Chartered Surveyors, who praised it for its "precise and beautifully detailed multi-sensory design". It was also a contender for the

National Eisteddfod of Wales The National Eisteddfod of Wales (Welsh language, Welsh: ') is the largest of several eisteddfodau that are held annually, mostly in Wales. Its eight days of competitions and performances are considered the largest music and poetry festival in Eur ...

Gold Medal for Architecture in 2017. It has been designed to create a relaxing environment volunteers, with large windows and timber structures.

Research

Cardiff University's School of Psychology created CUBRIC to facilitate interdisciplinary brain research, using multiple

neuroimaging Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Incre ...

machines and laboratory techniques. The centre houses: * 4 machines for

magnetic resonance imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio wave ...

(MRI) * magnetoencephalography (MEG) *

electroencephalography Electroencephalography (EEG) is a method to record an electrogram of the spontaneous electrical activity of the brain. The biosignals detected by EEG have been shown to represent the postsynaptic potentials of pyramidal neurons in the neocortex ...

(EEG) research * 5 electrical brain stimulation (EBS) laboratories * 10 cognitive method laboratories * the first connectome scanner outside the

United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territorie ...

, a Siemens 3 Tesla Connectom system. A range of cognitive neuroscience studies are being carried out at CUBRIC, covering areas such as sleep research and curiosity research. The centre aims to investigate neurological aspects of conditions such as

epilepsy Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical ...

Alzheimer's disease Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term me ...

schizophrenia Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdra ...

multiple sclerosis Multiple (cerebral) sclerosis (MS), also known as encephalomyelitis disseminata or disseminated sclerosis, is the most common demyelinating disease, in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This d ...

, and

dementia Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affe ...

. One of the centre's first major research projects in the new building involved the study of

Huntington's disease Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unst ...

. The connectome scanner generates a map of the axons in

white matter White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution ...

, connections of the brain, by measuring the nearby movement of water molecules to precision. Anomalous structures and changes to the brain's function, called biomarkers, can be identified through comparison to scans of healthy brains.

References

External links

*
Tour of CUBRIC Building

Simple Explanation of Connectome Scanning

Delivery of 7T MRI Scanner
{{Cardiff University Cardiff University Magnetoencephalography Medical imaging organizations Neuroimaging