CRIP2
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Cysteine-rich protein 2 is a
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''CRIP2''
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
. CRIP2 and the closely related
CRIP1 Cysteine-rich protein 1 is a protein that in humans is encoded by the ''CRIP1'' gene. Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 ( CS ...
are cysteine-rich proteins containing two
LIM domain LIM domains are protein structural domains, composed of two contiguous zinc fingers, separated by a two-amino acid residue hydrophobic linker. The domain name is an acronym of the three genes in which it was first identified (LIN-11, Isl-1 and M ...
s. They are highly expressed during cardiovascular development and act to bridge
serum response factor Serum response factor, also known as SRF, is a transcription factor protein. Function Serum response factor is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum ...
and
GATA Davionte Ganter, known professionally as GaTa, is an American rapper and actor known for his role in the FXX TV series ''Dave'', as well as for being the hype man for rapper Lil Dicky throughout his career as well as on the show. Early life a ...
proteins and stimulate smooth muscle target genes.


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