Corepressor interacting with RBPJ 1 is a
protein that in humans is encoded by the ''CIR1''
gene.
Interactions
CIR (gene) has been shown to
interact
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with
SNW1.
Model organisms
Model organism
A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workin ...
s have been used in the study of CIR1 function. A conditional
knockout mouse line called ''Cir1
tm3a(KOMP)Wtsi'' was generated at the
Wellcome Trust Sanger Institute.
Male and female animals underwent a standardized
phenotypic screen to determine the effects of deletion.
Additional screens performed: - In-depth immunological phenotyping
- in-depth bone and cartilage phenotyping
References
External links
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Further reading
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