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Chromatin assembly factor 1 subunit A is a
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''CHAF1A''
gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.


Function

Chromatin assembly factor I ( CAF-1) is a nuclear complex consisting of p50, p60 ( CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone tetramers onto replicating DNA in vitro (Kaufman et al., 1995). upplied by OMIMref name="entrez" />


Interactions

CHAF1A has been shown to
interact Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with: * ASF1A, * ASF1B, *
BLM BLM most commonly refers to: * Black Lives Matter, an international anti-racism movement and organization * Bureau of Land Management, a U.S. federal government agency BLM may also refer to: Organizations * BLM (law firm), United Kingdom and ...
, * CBX5, and *
MBD1 Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the ''MBD1'' gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequence ...
.


References


Further reading

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External links

* * {{gene-19-stub