Chromatin assembly factor 1 subunit A is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''CHAF1A''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
Chromatin assembly factor I (
CAF-1) is a nuclear complex consisting of p50, p60 (
CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone tetramers onto replicating DNA in vitro (Kaufman et al., 1995).
upplied by OMIMref name="entrez" />
Interactions
CHAF1A has been shown to
interact
Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...
with:
*
ASF1A,
[
* ASF1B,]
* BLM
BLM most commonly refers to:
* Black Lives Matter, an international anti-racism movement and organization
* Bureau of Land Management, a U.S. federal government agency
BLM may also refer to:
Organizations
* BLM (law firm), United Kingdom and ...
,
* CBX5, and
* MBD1
Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the ''MBD1'' gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequence ...
.
References
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
External links
*
*
{{gene-19-stub