CGS-12066A is a

drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...

which acts as a potent and selective

agonist An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...

for the 5-HT_1B

receptor Receptor may refer to: * Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse *Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a ...

with lower affinity for the three 5-HT₂ receptor subtypes. It is used for studying the role of the 5-HT_1B receptor in various processes including perception of pain and the sleep-wake cycle.

References

Serotonin receptor agonists Trifluoromethyl compounds Piperazines Quinoxalines {{nervous-system-drug-stub