CEP85L, for "Centrosomal Protein 85kDa-Like" is a gene which encodes a protein that has been identified as a breast cancer antigen. Nothing more is known of its function at this time. Three transcript variants encoding different isoforms have been found for this gene. It has been shown to be related to the

QT interval The QT interval is a measurement made on an electrocardiogram used to assess some of the electrical properties of the heart. It is calculated as the time from the start of the Q wave to the end of the T wave, and approximates to the time taken ...

in GWAS studies.

Pathology

Mutations of the CEP85L gene were associated with posterior predominant lissencephaly in a 2020 study.

Sources

{{Cite journal, last1=Kodani, first1=Andrew, last2=Kenny, first2=Connor, last3=Lai, first3=Abbe, last4=Gonzalez, first4=Dilenny M., last5=Stronge, first5=Edward, last6=Sejourne, first6=Gabrielle M., last7=Isacco, first7=Laura, last8=Partlow, first8=Jennifer N., last9=O'Donnell, first9=Anne, last10=McWalter, first10=Kirsty, last11=Byrne, first11=Alicia B., date=22 April 2020, title=Posterior Neocortex-Specific Regulation of Neuronal Migration by CEP85L Identifies Maternal Centriole-Dependent Activation of CDK5, journal=Neuron, volume=106, issue=2, pages=246–255.e6, doi=10.1016/j.neuron.2020.01.030, issn=1097-4199, pmc=7255387, pmid=32097629 Genes on human chromosome 6 Centrosome

Pathology

See also

Sources