CDPPB is a drug used in scientific research which acts as a
positive allosteric modulator
In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimulus. Some of them, like benzodiazepines, are drugs. The site that an allosteric modulator binds to ...
selective for the
metabotropic glutamate receptor subtype
mGluR5.
It has
antipsychotic
Antipsychotics, also known as neuroleptics, are a class of Psychiatric medication, psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but ...
effects in animal models,
and mGluR
5 modulators are under investigation as potential drugs for the treatment of
schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdra ...
,
as well as other applications.
References
Pyrazoles
Benzamides
Nitriles
MGlu5 receptor agonists
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