CAR-302,282 (302282, NSC-263548, α-(3-Methylbut-1-yn-3-enyl)mandelic acid 1-methyl-4-piperidyl ester) is an

anticholinergic Anticholinergics (anticholinergic agents) are substances that block the action of the neurotransmitter called acetylcholine (ACh) at synapses in the central and peripheral nervous system. These agents inhibit the parasympathetic nervous system ...

deliriant Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics and dissociatives such as LSD and ketamine, respectively, due to their primary effect of causing delirium, as opposed t ...

drug, invented under contract to

Edgewood Arsenal Aberdeen Proving Ground (APG) (sometimes erroneously called Aberdeen Proving ''Grounds'') is a U.S. Army facility located adjacent to Aberdeen, Harford County, Maryland, United States. More than 7,500 civilians and 5,000 military personnel work at ...

in the 1960s. It is a potent incapacitating agent with an ED₅₀ of 1.2μg/kg and a high central to peripheral effects ratio, and a relatively short duration of action compared to other similar drugs of around 6-10 hours. Despite its favorable properties it was relatively little researched compared to more high profile compounds from the series such as

EA-3167 EA-3167 is a potent and long-lasting anticholinergic deliriant drug, related to the chemical weapons, chemical warfare agent 3-Quinuclidinyl benzilate, 3-quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal experimen ...

and

EA-3580 EA-3580 is a potent anticholinergic deliriant drug with a fairly long duration of action, related to the chemical weapons, chemical warfare agent 3-Quinuclidinyl benzilate (QNB). It was developed under contract to Edgewood Arsenal experiments, Ed ...

References

Deliriants Muscarinic antagonists Incapacitating agents Piperidines Carboxylate esters Alkyne derivatives Tertiary alcohols {{hallucinogen-stub

See also

References