Cullin-associated NEDD8-dissociated protein 1 is a

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

that in humans is encoded by the ''CAND1''

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

Interactions

CAND1 has been shown to

interact Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizati ...

with: * CUL1, *

CUL2 Cullin-2 is a protein that in humans is encoded by the ''CUL2'' gene. Interactions CUL2 has been shown to interact with: * CAND1, * DCUN1D1, * RBX1, * SAP130, * TCEB2 and * Von Hippel-Lindau tumor suppressor The term ''von'' () ...

, *

CUL3 Cullin 3 is a protein that in humans is encoded by the ''CUL3'' gene. Cullin 3 protein belongs to the family of cullins which in mammals contains eight proteins (Cullin 1, Cullin 2, Cullin 3, Cullin 4A, Cullin 4B, Cullin 5, Cullin 7 and Cullin 9) ...

, *

CUL4A Cullin-4A is a protein that in humans is encoded by the ''CUL4A'' gene. CUL4A belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chro ...

, * CUL4B, *

DCUN1D1 DCN1-like protein 1 is a protein that in humans is encoded by the ''DCUN1D1'' gene. DCUN1D1 is amplified in several cancer types, including squamous cell cancers, and may act as an oncogenic driver in cancer cells. Interactions DCUN1D1 has bee ...

, and *

RBX1 RING-box protein 1 is a protein that in humans is encoded by the ''RBX1'' gene. Function This gene encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heter ...

Interactions

References

External links

Further reading