Calcium/calmodulin-dependent protein kinase type II delta chain is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that in humans is encoded by the ''CAMK2D''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
The product of this gene belongs to the
serine/threonine protein kinase family and to the
Ca2+/calmodulin-dependent protein kinase subfamily.
Calcium signaling is crucial for several aspects of
plasticity at
glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Four
alternatively spliced transcript variants that encode three different
isoforms have been characterized to date. Distinct isoforms of this chain have different expression patterns.
References
Further reading
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External links
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EC 2.7.11
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