Bisdemethoxycurcumin
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Bisdemethoxycurcumin is a
curcuminoid A curcuminoid is a linear diarylheptanoid, a relatively small class of plant secondary metabolites that includes curcumin, demethoxycurcumin, and bisdemethoxycurcumin, all isolated from turmeric (Turmeric, curcuma longa). These Chemical compou ...
found (along with the curcuminoids
curcumin Curcumin is a bright yellow chemical produced by plants of the ''Curcuma longa'' species. It is the principal curcuminoid of turmeric (''Curcuma longa''), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cosmetic ...
and
demethoxycurcumin Desmethoxycurcumin is a curcuminoid found in turmeric. Commercial grade curcumin contains a mixture of Curcuminoid, curcuminoids (desmethoxycurcumin 10–20%, bisdesmethoxycurcumin 5% or less). See also * Bis-desmethoxycurcumin * Curcumin Re ...
) in
turmeric Turmeric () is a flowering plant, ''Curcuma longa'' (), of the ginger family, Zingiberaceae, the rhizomes of which are used in cooking. The plant is a perennial, rhizomatous, herbaceous plant native to the Indian subcontinent and Southeast Asi ...
(''Curcuma longa''), but absent in Javanese turmeric (''Curcuma xanthorrhiza''). Bisdemethoxycurcumin is used as a
pigment A pigment is a colored material that is completely or nearly insoluble in water. In contrast, dyes are typically soluble, at least at some stage in their use. Generally dyes are often organic compounds whereas pigments are often inorganic compo ...
and
nutraceutical A nutraceutical or bioceutical is a pharmaceutical alternative which claims physiological benefits. In the US, "nutraceuticals" are largely unregulated, as they exist in the same category as dietary supplements and food additives by the FDA, unde ...
with antimutagenic properties. All three of the curcuminoids found in Curcuma longa have been shown to have antioxidant properties, but bisdemethoxycurcumin is more resistant than the others to
alkaline In chemistry, an alkali (; from ar, القلوي, al-qaly, lit=ashes of the saltwort) is a base (chemistry), basic, ionic compound, ionic salt (chemistry), salt of an alkali metal or an alkaline earth metal. An alkali can also be defined as ...
degradation. It was found to be effective in sensitizing PC cells resistance against gemcitabine.


See also

*
Curcumin Curcumin is a bright yellow chemical produced by plants of the ''Curcuma longa'' species. It is the principal curcuminoid of turmeric (''Curcuma longa''), a member of the ginger family, Zingiberaceae. It is sold as a herbal supplement, cosmetic ...
*
Desmethoxycurcumin Desmethoxycurcumin is a curcuminoid found in turmeric. Commercial grade curcumin contains a mixture of curcuminoids (desmethoxycurcumin 10–20%, bisdesmethoxycurcumin 5% or less). See also * Bis-desmethoxycurcumin * Curcumin Curcumin is ...


References


External links

* Curcuminoids Food colorings Phenolic dietary antioxidants Vinylogous carboxylic acids {{aromatic-stub